LCGC North America-11-01-2006

LCGC North America

Peaks of Interest

November 01, 2006

Departments

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Thar Technologies, Inc. (Pittsburgh, Pennsylvania) announced that it has entered into an agreement to develop supercritical fluid chromatography (SFC) applications with the Norwegian University of Life Sciences (As, Norway, NULS).

Setting Realistic Expectations for GC Optimization

November 01, 2006

GC Connections

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November 2006. This month, John Hinshaw addresses questions of instrument capabilities and chromatographers' expectations. In subsequent issues, he will discuss adjustment of hardware settings, optimization of column parameters, and data-handling issues. This is the first article in the recently released "GC Connections Resource Guide."

System Suitability and Validation for Chiral Purity Assays of Drug Substances

November 01, 2006

Peer-Reviewed Article

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Measurement of chiral purity is a necessary means of quality control for drug substances that exhibit chiral centers. This article describes a simple and practical approach to setting up system suitability and validation for chiral purity assays.

Analytical Method Transfer

November 01, 2006

Validation Viewpoint

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November 2006. The objective of a formal method transfer is to ensure that the receiving laboratory is well trained, qualified to run the method in question, and gets the same results - within experimental error - as the initiating laboratory. The development and validation of robust methods and strict adherence to well documented standard operating procedures is the best way to ensure the ultimate success of the method. This installment of "Validation Viewpoint" examines the analytical method transfer process, including protocol, documentation, and some possible chromatographic pitfalls to avoid.

Market Profile: The Global Laboratory Life Science and Analytical Instrument Industry

November 01, 2006

Departments

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The laboratory life science and analytical instrument industry is comprised of a large, diverse group of organizations that manufacture and distribute their products worldwide. However, overall industry sales are concentrated among a small set of companies. Approximately 950 firms are included in the industry, but only about 100 companies have sales above $50 million.