Advances in Biopharmaceutical Analysis
Modern Column Technologies for the Analytical Characterization of Biopharmaceuticals in Various Liquid Chromatographic Modes
Advances in Liquid Chromatography–Tandem Mass Spectrometry (LC–MS–MS)-Based Quantitation of Biopharmaceuticals in Biological Samples
Analyzing Host Cell Proteins Using Off-Line Two-Dimensional Liquid Chromatography–Mass Spectrometry
Higher Order Mass Spectrometry Techniques Applied to Biopharmaceuticals
Monoclonal Antibodies and Biosimilars — A Selection of Analytical Tools for Characterization and Comparability Assessment
With the top-selling mAbs evolving out of patent there has been a growing interest in the development of biosimilars. In demonstrating comparability to the originator product, biosimilar developers are confronted with an enormous analytical challenge. This article presents a selection of state-of-the-art analytical tools for mAb characterisation and comparability assessment.
Harnessing the Benefits of Mass Spectrometry for In-depth Antibody Drug Conjugates Analytical Characterization
Recent progress in high-resolution mass spectrometry (HRMS) and liquid chromatography–mass spectrometry (LC–MS) methods for the structural characterization of brentuximab vedotin and trastuzumab emtansine are presented.
Vol 28 No s10 LCGC Europe October 2015 Advances in Biopharmaceutical Analysis Supplement PDF
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