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Capillary electrophoresis (CE) is a small-scale separation technique based on differences in migration speed of species or compounds in an externally applied electric field.

Knauer Application Note

Antec application note

Thin-layer chromatography (TLC) provides analysts with a simple and quick method for examining the components in a mixture, and advances in the technique such as high performance TLC (HPTLC) offer higher resolution and greater reproducibility. Joining us for this discussion on TLC this month are Ned Dugan of Analtech, Inc., and Ling Bei and Dave Lentz of EMD Chemicals.

The new 6490 LC/MS provides the highest level of sensitivity for a wide range of critical applications such as environmental, food testing, and pharmaceutical analyses.

Kevin Altria, associate director at GlaxoSmithKline and CE Currents editor on the current status of CE as an effective analytical technique.

Mallinckrodt Baker will now be known as Avantor Performance Materials, company officials announced as they unveiled a new name and identity following the recent acquisition by an affiliate of New Mountain Capital.

The US Environmental Protection Agency (EPA) is proposing to add new and revised methods for water quality monitoring.

Following the accident at Chernobyl Nuclear Power Plant in 1986, the surrounding area remains substantially contaminated with radioactive isotopes. A study into the adaptations of the surrounding plant life has suggested that the plant proteomes remain largely unchanged by the radio contamination.

In recent years, improving productivity and cost-savings have become major initiatives in pharmaceutical discovery and development.

Gamma-Tocopherol is the dominant form of Vitamin E in many commonly ingested foods in the human diet, such as plant seeds and nuts. In the past, supplement companies have focused on the health benefits of alpha-tocopherol.

Chiral chromatography has become the preferred tool for enantiomer separations in the early stages of pharmaceutical development for the purpose of accurately identifying single pure enantiomers with pharmacologic, toxicological, and clinical information, as stipulated by the FDA.1

Although supercritical fluid chromatography (SFC) is not a new technique, preparative SFC is becoming increasingly more popular with advances in instrumentation, software and chemistry.

According to the FDA policy statement, developing stereoisomeric drugs, each enantiomer should be evaluated.

In the past decade, supercritical fluid chromatography (SFC) has been established as a cost-effective, sustainable, and green purification technology for pharmaceutical and related industries.

Bruker Application Note

PSS Application Note

Ron Majors interviews the inventors of QuEChERS to explore the sucesses, challenges and future potential of this innovative sample preparation technique.

Waters Application Note

A systematic approach to developing drug impurity profiling methods.

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Alasdair Matheson spoke to Gerda Morlock about her radical approach to boost the performance of ultrathin-layer chromatography.

The Royal Society of Chemistry has welcomed the British Government's decision to prioritise science in the Spending Review.

The benefits of using capillary electrophoresis to detect metal ions.

Click the title above to open the LCGC North America November 2010 regular issue, Vol 28 No 11, in an interactive PDF format.