November 17th 2023
Brandy Young, PhD, an analytical chemist with more than 15 years of experience, entered the cannabis industry in response to a recognized need for laboratory testing, aligning her expertise with the emerging demand in New York's active medical and adult-use cannabis programs. Here, she shares some background information on her Eastern Analytical Symposium (EAS) talk, which delves into the characterization of tetrahydrocannabinol (THC) isomers in cannabis products.
Chromatographers Get Into Cannabis
March 21st 2016Gas chromatography (GC) is an established and well-understood technique. As the cannabis industry grows, demand for analytical robustness is increasing for analytes such as pesticides, residual solvents, and terpenes. GC and GC coupled to mass spectrometry (GC–MS) are effective tools to address the demands of laboratories, growers, manufacturers, and consumers. This article provides an overview of the types of compounds that can be analyzed by GC, reviews the strengths and weaknesses of the analytical methods, and discusses areas of opportunity for chromatography.
Cannabinoid Quantitation Using an Agilent 6430 LC-MS-MS
April 16th 2015Sufficient resolution and peak shape for the targets can be achieved within an overall run time of 12.5 minutes. Additional validation studies confirmed that this method meets all criteria required for routine analysis of cannabinoids in whole blood.
Validation of a Cannabinoid Quantitation Method Using an Agilent 6430 LC-MS-MS
April 16th 2015A method was developed for the quantitation of Cannabinoids using an Agilent 6430 Triple Quadrupole LC/MS system. Validation showed that the LC/MS/MS method provides reliable results for the quantitation of THC, OH-THC, and carboxy-THC.
Stereoselective Metabolism of Cannabis Drugs Responsible for Toxicity
January 2nd 2014The variance in the toxic effects of designer cannabis drugs marketed throughout Europe and the USA as "K2" or "Spice" could be the result of stereoselective metabolism of enantiomers by lung and liver enzymes, according to a study published in Analytical Chemistry.