Cannabis Analysis

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THC Isomers in Cannabis: An EAS Interview with Brandy Young
THC Isomers in Cannabis: An EAS Interview with Brandy Young

November 17th 2023

Brandy Young, PhD, an analytical chemist with more than 15 years of experience, entered the cannabis industry in response to a recognized need for laboratory testing, aligning her expertise with the emerging demand in New York's active medical and adult-use cannabis programs. Here, she shares some background information on her Eastern Analytical Symposium (EAS) talk, which delves into the characterization of tetrahydrocannabinol (THC) isomers in cannabis products.

Gavel of judge lying on green leaves of marijuana closeup | Image Credit: © H_Ko -
EAS Coverage: Innovative Forensic Approaches to Cannabis Analysis: Streamlining Protocols and Overcoming Legalization Challenges

November 17th 2023

Trippy and psychedelic cannabis leaf. Hallucinations caused by cannabis or marijuana. Weird and wild cannabis background. The use of drugs to alter your mind. | Image Credit: © Jeremy Pawlowski -
EAS Coverage: The Characterization of D9-THC

November 17th 2023

Sam Heckle presenting his talk titled, "The Importance of Digestion Temperature on Trace Metals Analysis", at the 2023 Eastern Analytical Symposium (EAS).
EAS Coverage: Challenges Experienced in Cannabis Heavy Metal Analysis: Insights from Analytical Chemist Sam Heckle

November 17th 2023

Hands Trim Cannabis Plant Marijuana Indoor Farm | Image Credit: © The Colonel -
Ensuring Reliable Cannabis Analysis

September 25th 2023

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Analysis of Terpenes in Cannabis Using Headspace Solid-Phase Microextraction and GC–MS

May 1st 2017

As the legalization of medicinal cannabis continues to sweep across the United States, an urgent need has developed for fast, accurate and efficient analytical testing. In addition to testing for contaminants and potency, there is also interest in the determination of terpene identity and concentration levels present in different strains of cannabis. Terpenes have been shown to have therapeutic uses for treatment of different medical conditions ranging from cancer and inflammation, to anxiety and sleeplessness. It is believed that the combination of terpenes and cannabinoids in cannabis produce a synergistic effect with regards to medical benefits. The traditional testing method for terpenes in plant materials involves a solvent-based extraction followed by GC analysis. In this work, headspace solid phase microextraction (HS-SPME) was used to identify and quantify terpene content in cannabis. The HS-SPME method provided several advantages over solvent extraction in that it provided a cleaner analysis, free of interferences from co-extracted matrix, and was non-destructive to the sample. A cannabis sample of unknown origin was first analyzed qualitatively by HS-SPME and GC-MS. Spectral library matching and retention indices were used to identify 42 different terpenes. Quantitative analysis was then performed for several selected terpenes using spiked samples. Method accuracy was >90%, with reproducibility of