
- September 1999
- Volume 17
- Issue 9
- Pages: 854–864
Fast HPLC Method Development Using Interfaced Photodiode-Array and Ion-Trap MS Detection
With the goal of developing an analytical method for the fast analysis of vitamins in a complex matrix, the authors created a method that used in-line and complementary HPLC with photodiode-array and MS detection techniques.
The authors developed an analytical method for the fast analysis of vitamins in a complex matrix using in-line and complementary high performance liquid chromatography with photodiode-array and mass spectrometry detection techniques. The method development was significantly faster when the authors used both the UV-vis spectral scanning capability of a photodiode-array detector and the mass spectral scanning capability of an ion-trap mass spectrometer.
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Validation Viewpoint: The International Conference on HarmonizationNewsletter
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