On-line light scattering and viscometer detectors increase the information depth of GPC/SEC data and allow absolute molar masses and structures to be measured. However, even a set-up with advanced instrumentation is not parameter free and the inter-lab comparison of results is often sobering. Sometimes even the comparison of inter-lab results or the reproducibility is not acceptable. In most instances the reason for these deviations can be related to a wrong determination of the slice concentration. In contrast to conventional GPC/SEC, hyphenation with molar mass sensitive detection requires the precise and accurate knowledge of the mass in every chromatographic slice

The Column-10-17-2011

On-line light scattering and viscometer detectors increase the information depth of GPC/SEC data and allow absolute molar masses and structures to be measured.