Selected highlights from The Columns 2016 archives.
Jack Cochran’s “Practical GC” provided readers with practical advice and new experimental evidence for how to get the best results from their gas chromatography (GC) systems. This instalment looked at GC inlet liner choice for “shoot and dilute” GC.
Incognito debated the pros and cons of onshore support.
Raquel Garcia and Maria João Cabrita revealed the theory and practical applications of molecularly imprinted polymers (MIPs).
Koji Kosaka of the National Institute of Public Health, Japan, spoke with The Column about his use of high performance liquid chromatography (HPLC) to uncover the source of contamination in the Yodo River Basin in Japan, with the precursors of the carcinogen N-Nitrosodimethylamine (NDMA).
Protein biopharmaceuticals have seen an enormous growth in the last decade, and as a result, separation scientists are giving increased attention to methods for characterizing biopharmaceuticals. One powerful technique for analyzing proteins is two-dimensional liquid chromatography (2D LC). Gerd Vanhoenacker of the Research Institute for Chromatography (RIC) in Kortrijk, Belgium, spoke to The Column about his research into peptide mapping of therapeutic monoclonal antibodies (mAbs) using 2D LC.
Jean-Luc Veuthey and Alexandre GrandâGuillaume-Perrenoud revealed the latest developments in supercritical fluid chromatography (SFC) that are bringing the technique back to the limelight.
This article discussed the differences between the two techniques with particular emphasis on the requirements of their respective analytes.
Ion chromatography coupled to mass spectrometry (IC-MS) does not follow the same rules as coupling other modes of liquid chromatography to mass spectrometry (LC–MS). Leon Barron from the Analytical & Environmental Science Division, at King’s College London, UK, revealed some of the misconceptions surrounding IC and discussed contemporary trends and novel applications for this inventive technique.
Kevin A. Schug considered what the study of chemometrics and experimental design statistics can add to an analytical chemist’s work.
What is required to produce a highly efficient modern high performance liquid chromatography (HPLC) system/column combination? This instalment of the LCGC Blog explained more.