Interactive Charts: A Powerful New Tool for Understanding Chromatography Data
The interactive charting capabilities provide chemists with powerful new tools for analysing chromatography data more efficiently.
Chromatographers are generating more data than ever, as they adopt automation tools and faster methods to keep up with demands for increased productivity and for higher confidence in results. Managing all the data has become a major challenge because there is not enough time to scrutinize every chromatogram and result. Analysts need efficient ways to view the big picture, to spot significant items within the larger data set and to quickly analyse specific items that need closer examination.
A natural and effective solution is to present data graphically. Graphical representations allow large amounts of data to be presented in a compact format, facilitate comparison and make anomalies easy to detect. For example, the MiniPlots featured in the Chromeleon 7.1 chromatography data system (CDS) software presents a detailed miniature thumbnail image of each chromatogram in an injection sequence or query result. The user can scan dozens of chromatograms quickly and immediately spot any that differ in number of peaks, peak size or shape, background profile and so on.
Evaluating Antimicrobial Potential of Articaine Derivatives in Oral Infections with CMC
May 20th 2025Cell membrane chromatography (CMC) technology was used by researchers in screening efficacy and antibacterial ability of articaine (AT) derivatives in the pre-emptive treatment of oral infections.
Hydrophilic Interaction Chromatography (HILIC) and Direct Online Disruption of Lipid Nanoparticles
May 19th 2025Two proof-of-concept hydrophilic interaction chromatography HILIC) methods were developed in a joint study conducted by the University of Geneva (Switzerland), Sanofi, and the Waters Corporation—one for disrupting LNPs and retaining the mRNA, and another for detecting only unencapsulated mRNA to assess encapsulation efficiency. LCGC International spoke to Jonathan Maurer, first author of the paper that resulted from this study, about the methods and the efforts that led up to their development.
This article discusses how integrating seven prioritization strategies can enhance compound identification, support environmental risk assessment, and accelerate decision-making.
