Recent Advances in Microfluidic Liquid Chromatography

A publication in TrAC Trends in Analytical Chemistry has covered the recent advances in microfluidic liquid chromatography (from January 2013 through April 2015). Featuring a comprehensive guide to the latest technological improvements in both device robustness, instrument integration, efficiency, and portability, the review covers low-cost separation techniques in the form of monolithic stationary phases in polymeric chips and postulates on the development of disposable, one‑time use chromatographic columns. The possibilities of 3D printing and the impact this technology could have in terms of substrate fabrication or the manufacturing of a fully integrated instrument–column hybrid are also discussed. 

For more information please see J.P. Grinias and R.T. Kennedy, TrAC, Trends Anal. Chem. 81, 110–117 (2016) doi:10.1016/j.trac.2015.08.002