Recent Advances in the Preparation and Application of Monolithic Capillary Columns
Researchers from the China Pharmaceutical University in Nanjing, China, have published a review of the recent advances in the preparation and application of monolithic capillary columns in separation science.
Researchers from the China Pharmaceutical University in Nanjing, China, have published a review of the recent advances in the preparation and application of monolithic capillary columns in separation science. The publication features a review of three novel preparation strategies for the preparation of capillary monoliths, including ionic liquid-based approaches, nanoparticle-based approaches, and a “click chemistry” approach. Furthermore, the article summarizes the recent strategies utilized in constructing different capillary monoliths for enantiomeric separation, and describes the advancement of capillary monoliths for complex sample analysis.
For more information please see T. Hong et al., Anal. Chim. Acta 931, 1–24 (2016). doi:10.1016/j.aca.2016.05.013
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
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Top Execs from Agilent, Waters, and Bruker Take the Stage at J.P. Morgan Healthcare Conference
January 16th 2025The 43rd Annual Healthcare J.P. Morgan Healthcare Conference kicked off in San Francisco earlier this week. Here’s what top executives from Agilent, Bruker, and Waters, discussed during the event.
