|Articles|February 1, 2012
- The Column-02-01-2012
- Volume 8
- Issue 2
Using MS Data for Peak Tracking in Computer Supported HPLC Method Development
A systematic way to develop HPLC methods consists of building up and running a useful set of experiments (DOE, design of experiments) to evaluate the influence of several factors or method conditions on the selectivity of a chromatogram. The crucial part here is the peak tracking between the chromatograms.
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A systematic way to develop HPLC methods consists of building up and running a useful set of experiments (DOE, design of experiments) to evaluate the influence of several factors or method conditions on the selectivity of a chromatogram. The crucial part here is the peak tracking between the chromatograms. It has been shown that under most conditions peak areas can be used to identify peaks of the same compound in different chromatograms. However, this technique also has some limitations that will be discussed in this article.
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Life Science Instrumentation for Small Molecule Analysisalmost 14 years ago
Ancient smoke signalsalmost 14 years ago
Salt desertsalmost 14 years ago
Vehicle document forgeryalmost 14 years ago
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