Application Notes: Environmental

A fast analytical method including both sample preparation and LC–ƒMS/MS analysis of ibuprofen in human plasma.

Implementing a peptide screening SPE plate determines the appropriate choice for a wide range of chemically diverse peptides.

The optimized dual solid phase extraction (SPE) method was developed to significantly reduce the surfactant background from formulated drug products.

A HILIC solid phase extraction (SPE) and LC method that results in sensitive, effective, and a time savings for the clean-up of N-Glycans.

The development of a selective and rugged LC–MS/MS method for the quantitation of Amlodipine enantiomers in human plasma.

GenX, along with 24 other PFASs, are analyzed simultaneously to achieve sub-ppt reporting limits.

A reliable and efficient method was developed to determine the concentration sterols in olive oil by GC-FID.

The development of a selective and rugged LC–MS/MS method for the quantitation of Amlodipine enantiomers in human plasma.

SPE is used in combination with LC–MS/MS to analyze a panel of opiates from a urine sample.

Mycotoxin in grain are extracted using SPE to removes interferences followed by a rapid LC–MS/MS method.

GenX, along with 24 other PFASs, are analyzed simultaneously to achieve sub-ppt reporting limits.

A fast analytical method including both sample preparation and LC–ƒMS/MS analysis of ibuprofen in human plasma.

SPE is used in combination with LC–MS/MS to analyze a panel of opiates from a urine sample.

Optimize the LC–MS/MS workflow by using a SPE solution that provides in-well urine hydrolysis to save time.

Optimize the LC–MS/MS workflow by using a SPE solution that provides in-well urine hydrolysis to save time.

A reliable and efficient method was developed to determine the concentration sterols in olive oil by GC-FID.

This applicate note presents the use of an automated solid-phase extraction (SPE) system to improve the accuracy and precision of semivolatile extractions, in compliance with EPA Method 8270.

This application note outlines the performance benefits achieved with UCT’s LipiFiltr® cleanup cartridge for the analysis of pesticides in oil-based cannabis products using LC–MS/MS analysis.

New separation techniques for the analysis of polar and ionic analytes have aroused great interest in the field of metabolomics and environmental investigation in the past two decades. Hydrophilic interaction liquid chromatography (HILIC) is a promising tool to address this challenge. HILIC separation is based on the polarity of analytes, which generally show stronger retention with increasing polarity according to the HILIC separation mechanism. Furthermore, the high content of organic solvent in the mobile phase leads to good ionization properties in the electrospray ionization (ESI), and consequently enhances the detection sensitivity by hyphenated mass spectrometry (MS) detector.

Microwave extraction becomes faster and easier with the new Milestone ETHOS X with its FastEX-24. This application note shows the use of Milestone technology for extraction of dioxins from environmental matrices, with emphasis on one of the most common challenge of this application: the carryover effect. The unique design of the FastEX-24 rotor with disposable glass vials allows easy and efficient dioxin extraction, and other organic pollutants, to be performed, avoiding any memory effect. The FastEX-24 simplifies the routine pollutants extraction process and provides superior productivity at lower costs.

This application note will present the data collected as part of the demonstration of disk solid phase extraction validation for US EPA method 625.1.

By switching to a Raptor C18 column, labs can process more samples per hour while still meeting fluorochemical method requirements.