Application Notes: Environmental

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The Application Notebook

New separation techniques for the analysis of polar and ionic analytes have aroused great interest in the field of metabolomics and environmental investigation in the past two decades. Hydrophilic interaction liquid chromatography (HILIC) is a promising tool to address this challenge. HILIC separation is based on the polarity of analytes, which generally show stronger retention with increasing polarity according to the HILIC separation mechanism. Furthermore, the high content of organic solvent in the mobile phase leads to good ionization properties in the electrospray ionization (ESI), and consequently enhances the detection sensitivity by hyphenated mass spectrometry (MS) detector.

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The Application Notebook

Microwave extraction becomes faster and easier with the new Milestone ETHOS X with its FastEX-24. This application note shows the use of Milestone technology for extraction of dioxins from environmental matrices, with emphasis on one of the most common challenge of this application: the carryover effect. The unique design of the FastEX-24 rotor with disposable glass vials allows easy and efficient dioxin extraction, and other organic pollutants, to be performed, avoiding any memory effect. The FastEX-24 simplifies the routine pollutants extraction process and provides superior productivity at lower costs.

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Special Issues

With the recent legalization of cannabis in several states, there is a growing need for robust, reliable, and cost-effective analytical methods to facilitate routine testing for potency and contaminants. Here we present an LC–MS/MS method that uses the budget-friendly SCIEX Triple Quad 3500 LC–MS/MS system for the simultaneous detection and quantification of cannabinoids, pesticides, and mycotoxins in cannabis products using the Scheduled MRM algorithm.

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The Application Notebook

Initial precision was demonstrated by spiking four 1-L volumes with one Snip and Pour pre-measured standard, each (40 mg). The data for four replicates was collected for 47 mm Disks and 100 mm Disks. The average percent recovery is excellent and meets the criterion specified of 83–101% HEM recovery for both size disks. The standard deviation is better than the criterion specified of 11% for HEM.

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The Application Notebook

Hamilton PRP-X100 and PRP-X110 are the perfect solution for anion analysis in water or environmental samples. The robust design and covalent surface modification of the packing material lead to a highly increased lifetime as compared to the competition. The production process is compliant to ISO 9001 ensuring an outstanding column-to-column and lot-to-lot reproducibility.

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Special Issues

The US EPA has implemented an exposure research program aimed at conducting drinking water research on methods as part of the Microbiological and Chemical Exposure Assessment. This research is aimed at evaluating the chemical pollutants and their role and levels in which there is an unacceptable risk to either humans or wildlife, as well as evaluating the methodologies currently being used to determine levels of chemical pollutants.