Application Notes: GC-MS

SIFT-MS has unique advantages in air quality measurement applications. It enables environmental incidents to be detected and remedied before they escalate.

This application note demonstrates that automated headspace-SIFT-MS analysis has the potential to screen larger sample numbers for the volatile MOH fraction, providing a rapid indication of packaging material contamination. As benzene has also recently been found to be problematic in commercial products, Headspace-SIFT-MS can screen over 220 samples per day for volatile MOSH and MOAH compounds – nearly seven-fold more samples than the routine liquid and gas chromatography method.

Quantitative analysis of volatile nitrosamine impurities in drug products is simplified using SIFT-MS and has a 3X throughput advantage over chromatographic methods.

In this study, Syft Tracer analyzed the same samples in 9 hours that took 5 chromatographic systems 24 hours to complete and still had capacity to spare.

Featured Application: Semivolatiles on Rxi-SVOCms

Automated high-capacity sorptive extraction with GC–MS for screening wine, at ppb levels, for two yeast-derived spoilage compounds in wine.

Mesylate and besylate are potentially genotoxic impurities in pharmaceuticals. This app note introduces analysis of sulfonic acid esters utilizing Shimadzu's GCMS-QP.

Untargeted comparison of flavour profiles of popular brand soft drinks using immersive sorptive extraction, GCxGC–TOF-MS and chemometrics.

USP General Chapter <1469> ensures appropriate control of NSAs in drug products. This application replicates NSA determination in APIs using Shimadzu's GCMS-TQ8050 NX.

Demonstrating how commercially available TD equipment is used to monitor CF4 & other products of incomplete destruction (PIDs) resulting from PFAS removal technologies.

This study investigates the performance of a high-throughput automated thermal desorption instrument coupled to GC–MS/MS for PFAS analysis.

This application note utilises SCION's GC-MS to test for cannabinoids, providing method conditions and sample preparation techniques to validate methods.

Measuring PFAS pollution in ambient air with TD–GC–MS/MS at concentrations low as 2 pg/m3. Each of 19 targeted compounds had linear calibration with high repeatability.

This application note provides insights into how to monitor the different cannabis strains, and showcases how the Horwitz ration can be a useful tool in this analysis.

Discover how Headspace GC-MS is used to test cannabis samples for residual solvents and pesticides in this application note.

Passive sampling of plant volatiles using TF-SPME and GERSTEL Twister, respectively, is compared with active sampling onto PDMS foam- and TenaxTA-filled Tubes

Lipid oxidation generates off-odors in food, edible oils, and fats. DHS or Thermal Extraction-GC–MS/O using Sensory Directed Analysis quickly identifies off-odors

An analytical approach combined with PCA is compared to sensory-directed analysis (SDA) for differentiating honey from multi-floral, wildflower, and clover sources

Determination of flavors in smoothies using standard- and solvent-swollen Twister® stir bars, liquid desorption, and LVI-GC/MS for enhanced recovery of polar compounds

Smart Ramped Pyrolysis-GC–MS analysis of forensic samples such as paint, adhesive tape, and mascara gives maximum information in a single run without method development

This application note demonstrates how splitless micro-furnace pyrolysis increases the sensitivity of microplastic measurements.

Air quality measurement: Continuous, cryogen-free on-line monitoring of PAMS in ambient air using hydrogen carrier gas using EPA PAMS method.

Tube-based thermal desorption for monitoring chemical warfare agents Malathion, Russian VX and mustard gas at ultratrace levels without degradation or losses.

This app note describes automated, high-performance GC–MS analysis of humid 'air toxics' samples in canisters, using a cryogen-free system for preconcentration and TD.

This application note shows the robust, reproducible analysis of trace VOCs in hydrogen fuel by TD–GC–MS/SCD.

Using thermal desorption–GC–MS is to address multiple challenges in the detection of microplastics in different salt samples.

This study investigates the performance of a high-throughput automated thermal desorption instrument coupled to GC–MS/MS for PFAS analysis.

TD–GC–MS analysis of VOCs in air using H2 carrier gas meets all the performance criteria cited in US EPA Method TO-17, including linearity, reproducibility & MDLs.