Application Notes: GC-MS

Fast GC/MS method for SVOC per EPA 8270E: 87 compounds analyzed in ~14 min with high accuracy, compliance, and repeatability

Single-run analysis of 117 VOCs including PAMS, air toxics and OVOCs, delivering compliant performance at 100% humidity without cryogen or extended cycle times.

Reliable TO-15 analysis of air toxics from canisters at up to 100% humidity, achieving low ppt detection limits with robust water management and consistent performance.

Enthalpy Analytical improves throughput and reliability for humid environmental air samples, overcoming moisture challenges while maintaining productivity and data quality.

Automated TD–GC–MS analysis of air toxics using sorbent tubes, delivering compliant TO-17 performance, low detection limits, and flexible sample re-analysis.

Continuous cryogen-free monitoring of ozone precursors and polar VOCs, enabling low detection limits and reliable analysis of humid air without compound losses.

PFAS in air: Validating ASTM D8591 for measuring airborne fluorotelomer alcohols, achieving low pg detection limits with robust data quality.

The last AppNote in this Newsletter shows how liquid-liquid extraction of xylazine and medetomidine in plasma and urine can be fully automated and seamlessly combined with LC-MS/MS analysis. All critical steps - including extraction, mixing, centrifugation, evaporation, and solvent exchange - are performed by the MPS, enabling high-throughput workflows with excellent accuracy and precision at low concentration levels.

This AppNote highlights how salting-out assisted liquid-liquid extraction (SALLE) can be fully automated for the determination of bisphenol A (BPA) in beverages. The study demonstrates how automation removes sample-prep bottlenecks while ensuring consistent, robust results across a wide range of beverage matrices.

This AppNote shows how manual liquid-liquid extraction can be directly translated into a fully automated workflow using the GERSTEL MPS. The result: highly reproducible data, reduced solvent exposure, and far less hands-on time for laboratory staff. Even complex steps such as mixing, evaporation, and reconstitution are handled reliably - making LLE more efficient and better suited for routine analysis.

Fully automated determination of 3-MCPD, 2-MCPD and glycidol esters in edible oils using ISO 18363-4 with automated sample preparation and GC-MS/MS detection.

Discover how the PET Recycling Team is setting new standards in recycled material performance using the GC 2400 systems to transform quality control process and accelerate your sustainability goals

Rapid HS-GC/FID method quantifies ethanol in food and drink with high sensitivity, robust calibration, and compliance across global standards.

Dynamic Focusing enables cryogen-free trapping of VOCs and VVOCs from ambient air, delivering method-compliant sensitivity and precision for TO-17 and ISO 16000-6.

Fast GC/MS method analyzes 76 pesticides per EPA 525 in under 8.5 min using GCMS 2400, ensuring compliance, sensitivity, and resolution.

Discover a robust GC headspace method for accurate, low-carryover detection of residual NMP in Li-ion batteries using the GC 2400 and HS 2400M systems.

Fast GC/MS method for SVOC per EPA 8270E: 87 compounds analyzed in ~14 min with high accuracy, compliance, and repeatability

A robust HS-GC-FID workflow on the GC 2400™ and HS 2400™ enables accurate, reproducible USP 467 residual solvent analysis with streamlined, 21 CFR Part 11–compliant data control.

Quantify 1,4-dioxane in water and cosmetics with trace-level accuracy using PerkinElmer's GCMS Headspace Sampler.

Learn how to prevent contamination in pipetting. This guide covers pipette-to-sample, sample-to-pipette, and sample-to-sample risks, with best practices like filter tips and sterile techniques.

Prevent contamination in pipetting with best practices to avoid pipette-to-sample, sample-to-pipette, and sample-to-sample risks. Learn how filter tips and sterile techniques safeguard results.

Overcome common challenges in 3D cell culture pipetting. Learn tips for handling viscous hydrogels, transferring spheroids, reducing contamination, and improving throughput with the right techniques.

Discover best practices for reproducible 3D cell culture workflows. Learn how Picus® 2 pipettes and GrowDex® hydrogels improve accuracy, reduce variability, and streamline sample prep.

Shows how TD-GC-MS enables rapid in-house screening of chemical emissions from construction and consumer materials.

Outlines a method for detecting trace PFAS emissions from packaging and cookware using dynamic headspace with TD-GC-MS.

Presents a TD-GC-MS method for ppt-level detection of PAHs in air, offering a simpler alternative to solvent-based protocols.

Details how sorbent-based breath sampling combines with TD-GC-MS supports VOC biomarker discovery and route screening.

A practical overview of the technique introduces the principles, instrumentation, and typical sample of workflows used in TD-GC-MS.