Koen Sandra is the editor of “Biopharmaceutical Perspectives”. He is CEO at RIC group and visiting professor at Ghent University. He is also a member of LCGC Europe’s editorial advisory board.
Advances in Biopharmaceutical Analysis
Analyzing Host Cell Proteins Using Off-Line Two-Dimensional Liquid Chromatography–Mass Spectrometry
Monoclonal Antibodies and Biosimilars — A Selection of Analytical Tools for Characterization and Comparability Assessment
With the top-selling mAbs evolving out of patent there has been a growing interest in the development of biosimilars. In demonstrating comparability to the originator product, biosimilar developers are confronted with an enormous analytical challenge. This article presents a selection of state-of-the-art analytical tools for mAb characterisation and comparability assessment.
The Power of Liquid Chromatography–Mass Spectrometry in the Characterization of Protein Biopharmaceuticals
This article highlights some selected examples of the power of liquid chromatography combined with mass spectrometry (LC–MS) in the development of protein biopharmaceuticals.
Green Chromatography (Part 1): Introduction and Liquid Chromatography
Part one focusses on ways of reducing and replacing solvents commonly used as mobile phases