LCGC Staff

In his plenary lecture at HPLC 2023, Michal Holčapek presented his team's findings on how chromatography can help scientists record the human lipodome and better our understanding of diseases.

Gunda Köllensperger spoke at HPLC 2023 about how using U13C-isotopically labelled biomass extracts can change how scientists approach metabolomics.

A talk by Alberto Cavazzini of the University of Ferrara at HPLC 2023 focused on various types of chiral stationary phases (CSP) in efforts to improve efficiency.

In this HPLC 2023 keynote lecture, Mario Thevis discusses how chromatographic–mass spectrometric approaches have led to important advancements in sports drug testing programmes.

At HPLC 2023, Hyukju Kwon hosted a lecture on the roles LC–MS and artificial intelligence can have in autonomous material discovery.

Peter Schoenmakers of the University of Amsterdam presented a talk at HPLC 2023 on multidimensional liquid chromatography (LC).

At HPLC 2023, LCGC spoke with Kevin Pagel of Freie Universität in Berlin, Germany. These clips comprise one of several HPLC interviews that were conducted at the conference.

At HPLC 2023, LCGC spoke with Peter Schoenmakers of the University of Amsterdam. These clips comprise one of several HPLC interviews that were conducted at the conference.

At HPLC 2023, LCGC spoke with Gérard Hopfgartner of the University of Geneva. This clip contains one of several HPLC interviews that were conducted at the conference.

At HPLC 2023, LCGC spoke with Oliver Fiehn of the University of California, Davis. This clip contains one of several HPLC interviews that were conducted at the conference.

Award presentations and plenary lectures were some of the attractions as the annual conference got underway on Sunday.

At HPLC 2023, Oliver Fiehn of the University of California explained results gathered from a device that can be used during daily digestion.

In a session on omics at HPLC 2023, Robert T. Kennedy of the University of Michigan revealed how scientists are taking advantage of new developments and cutting down on analysis time.

At HPLC 2023, Kelly Zhang gave a lecture on how machine learning can help further our understanding of the characterization of lipid nanoparticles.

At HPLC 2023, Matthias Pursch presented his findings on using UHPLC and SEC to monitor small molecule and polymer reactions in real time.

A new study reveals that real-time library searching significantly improves the structural characterization of glycerophospholipids and sphingomyelins, offering enhanced selectivity and comprehensive analysis. By utilizing real-time identifications to trigger targeted MSn analyses, researchers gain deeper insights into these crucial lipid species.

Researchers have discovered diacylglycerols as potent biomarkers for the rapid diagnosis of breast cancer, using mass spectrometry imaging. This breakthrough study offers new possibilities for improved intraoperative assessment and personalized treatment strategies.

Scientists have developed a breakthrough MDLC–MS method for in-depth characterization of charge variants in therapeutic antibodies. The innovative approach enables the detection and evaluation of rare charge variants, facilitating improved safety and efficacy in antibody development.

New research emphasize the importance of identifying metabolite interference in LC–MS targeted metabolomics analysis to ensure accurate results. The study highlights the need for thorough investigation and resolution of metabolite interferences for reliable metabolite measurement in targeted metabolomics.

Mixed-mode cationic exchange (MCX) sorptive tapes combined with direct infusion mass spectrometry enable selective extraction and rapid analysis of cationic compounds in complex samples, such as opioids in saliva.

A research team has developed a fast and sensitive method using UHPLC–MS/MS to simultaneously detect the nematicide fluensulfone (FSF) and its two major metabolites in different agricultural soils, providing valuable insights into the environmental behavior of FSF in soil systems.

New method enables comprehensive analysis of secondary formation markers in ambient organic aerosols, providing valuable insights into atmospheric pollutants using HPLC–ESI-TOF-MS.

The development of a newly-designed Girard's reagent, HBP, as charged isobaric mass tags has enabled selective capture and sensitive detection of aldehyde metabolites. The LC–dNLS-MS/MS screening approach using this reagent has successfully facilitated the discovery of natural aldehydes and their profiling in complex samples.

Researchers have developed an innovative strategy for compound annotation in offline 2D-LC–MS analysis. The approach combines hand-in-hand alignment with targeted molecular networking (TMN) and was successfully applied to analyze the chemical profile of Yupingfeng (YPF), a traditional Chinese medicine prescription, resulting in the identification of 497 compounds and demonstrating its efficiency and scalability in complex sample analysis.

A temperature-controlled cryogenic distillation and gas chromatography, atom trap measurement system is used for precise analysis of atmospheric 85Kr abundance. This advanced technology enables online monitoring with high sensitivity and reduced sample size requirements.

Adjustable polyacrylamide stationary phases developed by researchers enhance separation performance in liquid chromatography, according to a recent publication. The study demonstrates the synthesis of vinyl modified silica and the successful preparation of polyacrylamide modified silica (PAM-SIL) stationary phases, allowing for fine control of separation performance.

A newly developed UHPLC–MS/MS method allows for the accurate analysis of bioactive compounds, including apigenin, apigenin 7-glucoside, and chlorogenic acid, in goat serum.

In a talk at ASMS 2023, Stephanie Rankin-Turner of the Johns Hopkins Bloomberg School of Public Health detailed how thermal desorption–gas chromatography–mass spectrometry (TD–GC–MS) analyzed the body odor of humans to quantify mosquitos' attraction to them.

Here, we summarize the 17 Tuesday evening workshops that took place from 5:45–7:00 pm at ASMS.

The latest research news and news in brief.