LCGC Staff

Articles by LCGC Staff

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A team of researchers has investigated strategies to overcome sample introduction challenges in hydrophilic-interaction chromatography (HILIC). By employing techniques such as pre-column dilution and selecting alternative organic solvents, they successfully addressed the issues related to injection solvent strength, resulting in improved peak symmetry and separation efficiency in HILIC analyses.

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Researchers have recalibrated polyparameter linear free energy relationships (PP-LFERs) for low-density polyethylene (LDPE) passive samplers. By utilizing a robust regression method and reliable partition coefficients and solute descriptors, the recalibrated models exhibited improved predictive performance, accurately estimating LDPE-water and LDPE-air partition coefficients across a wide range of compounds.

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Researchers have synthesized a chiral metal-organic framework (MOF) called L-histidine-zeolitic imidazolate framework-67 (L-His-ZIF-67) for enantioseparation of drugs in capillary electrochromatography. The chiral MOF demonstrated excellent separation efficiency for five chiral drugs, offering promising possibilities for pharmaceutical analysis and quality control.