LCGC Staff

An upcoming study revealed more information about the folding dynamics of i-motif DNA structures.

A team of researchers have developed a method to analyze mRNA poly(A) tail length and heterogeneity more efficiently.

On 1 October 2023, Alexandra Knauer was awarded the Order of Merit of the State of Berlin by Governing Mayor Kai Wegner.

Researchers from the Swedish University of Agricultural Sciences (SLU) and the Technical University of Munich have conducted a study on the sorption behaviour of per- and polyfluoroalkyl substances (PFAS) in various organic soil horizons.

The Schauenburg Analytics Group (Bridgend, UK), which consists of Markes International and SepSolve Analytical, has appointed Nigel Fry as its chief executive officer (CEO).

The Green Analytical Chemistry Workshop (1st TGAC) will be held 5–6 February 2024, at Novotel Paris-Charenton, Paris, France. Here's a glimpse at what attendees can look forward to.

In a recent study, researchers used a novel ultrahigh-performance liquid chromatography (UHPLC) method to analyze Lingyang Qingfei pills (LQPs) chemical constituents and metabolites.

Researchers from Vrije Universiteit Brussel and Sapienza Università di Roma shed light on the characteristics of mass transfer paths in liquid chromatography.

In a recent study, SHS-GC–MS was used to analyze children’s plastic toys to ensure their safety and efficacy.

These molecules have garnered attention for their potential to target currently undruggable disease-associated targets.

A recent study highlights the use of predictive tools to purify antibodies.

Researchers have developed a 3D tumor-immune cell coculture spheroid model combined with mass spectrometry (MS) imaging-based spatially resolved metabolomics, offering insights into metabolic alterations during antitumor immune responses.

In a recent study, a novel chiral column, based on a CC19-R porous organic cage, promises to enhance enantioselective HPLC separations.

A novel lenvatinib stability-indicating method, developed through a quality by design (QbD) approach and embracing principles of green chemistry, offers a robust solution for ensuring the drug's stability under various conditions.

Researchers have developed a meticulous method for analyzing impurities in a product used for early treatment of breast cancer in premenopausal and perimenopausal women, shedding light on the product’s degradation pathways.

A comparison between two types of detectors—variable wavelength (VWD) and fluorescence (FLD)—in quantifying azoxystrobin from water samples was conducted.

Researchers have developed a method for the simultaneous determination of betulinic acid, oleanolic acid, and ursolic acid in jujube extract, utilizing high performance liquid chromatography with ultraviolet detection (HPLC–UV) coupled with multilayer perceptron networks, offering a more efficient alternative to classical HPLC techniques.

A recent study enhances capillary electrophoresis by streamlining the preparation process for linear polyacrylamide (LPA)-coated capillaries.

In a recent study, researchers used a dual-isotope labeling method to help improve our understanding of lipid metabolism.

Researchers from the University of Florida have employed gas-phase charge inversion ion/ion reactions to distinguish isobaric lipids in imaging mass spectrometry, offering enhanced molecular specificity for analyte identification.

In a recent study, researchers from Technische Universität Dresden have unveiled a new method for the simultaneous quantification of kynurenine-related metabolites in biological matrices.

Researchers at two US colleges have utilized ion mobility spectrometry–mass spectrometry (IMS-MS) to analyze nonenzymatic posttranslational modifications and peptide cleavages in a single peptide system, revealing insights into critical biomarkers for age-related diseases.

Researchers in Tianjin, China, have employed all ion unfolding–ion mobility–mass spectrometry (AIU–IM–MS) to enhance the differentiation of therapeutic polyclonal antibodies, offering insights into improvements in conformational stability and advantages in cost-effectiveness.

Recent advances in the analysis of odorous substances in drinking water disinfection are crucial for maintaining water quality and public health.

A study conducted at the University of Almeria, Spain, has developed an automated micro-solid-phase extraction (µSPE) clean-up method for pesticide residue analysis in various spice samples, including paprika, curry, turmeric, dry chili, and black pepper, using LC–MS/MS.

Valérie Pichon's review in Analytical and Bioanalytical Chemistry delves into sophisticated liquid chromatography techniques for detecting albumin adducts, vital biomarkers in retrospective mustard agent exposure monitoring, offering a broader window of detection than urine-based methods.

A research team assessed the performance of electron activated dissociation (EAD) in comparison to collision-induced dissociation (CID) using a fast-scanning quadrupole time-of-flight (QTOF) mass spectrometer.

A comprehensive analytical approach utilizing online two-dimensional liquid chromatography coupled with hybrid linear ion trap orbital trap mass spectrometry, has enabled the in-depth analysis of Huangqi Guizhi Wuwu decoction, identifying 170 chemical constituents and offering insights into its complex chemical composition and potential therapeutic properties.

Researchers have developed a highly sensitive and cost-effective HPLC-UV method for simultaneously detecting 36 D/L-amino acids in foods, opening new avenues for food quality control and shedding light on the significance of D-amino acids in nature.

Liquid chromatography-mass spectrometry (LC–MS) often falls short in differentiating between isomeric and isobaric lipid species in complex biological samples.