Shimadzu Corporation

Demonstrated in this work is the use of bioinert UHPLC and LC-MS to analyze oligonucleotides accurately and reproducibly, allowing for faster development and quality control.

In this poster, a triple quad LC-MS was used to quantify per- and poly-fluoroalkylated substances (PFAS) to meet the requirements set by the EPA 1633 draft method, which describes the analysis of forty PFAS in wastewater, solids, biosolids, and tissue samples.

This article shows that the N-glycans of ACE2, a receptor of SARSCoV-2, and their sialic acid linkage types can be easily evaluated using MALDI-TOF analysis.

This app note introduces the use of the Nexera XS inert UHPLC, which utilizes a metal-free flow path for accurate and reproducible analysis of nucleotides.  

This technical report covers how a column packed with small particle material can be used to optimize an analytical method for monoclonal antibody aggregates. 

This app note introduces an analytical method for the separation of oligonucleotides of different length by ion-exchange chromatography using the Nexera XS Inert. 

This app note covers aggregate analysis using a Shimadzu Shim-pack™ BioDiol size-exclusion chromatography column with the Nexera XS inert UHPLC.  

This application introduces the automated analysis of fluorescent diastereomers of the proteinogenic D/L-amino acids using derivatizing reagents with chiral structures.

This podcast will examine peak deconvolution with photodiode array detectors and how a unique software function can separate peaks that are not resolved on-column, yielding better detection results and minimizing method development and analysis time. The podcast will explore the development of this tool with a leading pharmaceutical company and provide examples of how it can have an impact across a wide range of disciplines in the pharma/biopharma arena, from development to production.

This article introduces a comprehensive fractionation for both UV absorbing and non-UV absorbing compounds using a newly designed PDA-ELSD triggered preparative LC.  

This application demonstrates the efficiency, throughput, and reliability of a dual-injection system for finished pharmaceutical products and in-process APIs.

This application demonstrates a reliable GC–MS/MS method for analysis of nitrosamine drug products including the three impurities NDMA, NDEA, and NDBA listed by US FDA.

***Live: Day One: Wednesday, February 10, 2021 at 9:30am EST - 4:30pm EST *** Day Two: Thursday, February 11, 2021at 9:30am EST - 4:30pm EST *** Join us for this two-day virtual symposium on data integrity with renowned experts Bob McDowall, Chris Burgess, and Mark Newton. This event is aimed at chromatographers and quality assurance professionals who have a working knowledge of data integrity within a regulated GXP laboratory. ***On demand available after final airing until Feb. 10, 2022***

***Live: Two Day Event! Day One: Thursday, Oct. 22, 2020 10am EDT | 12:30pm EDT | 2pm EDT & Day Two: Friday, Oct. 23, 2020 10am EDT | 2pm EDT *** In this two-day online event, speakers will discuss theory and applications of gas chromatography (GC) and high performance liquid chromatography (HPLC). We have a morning and afternoon session each day, plus a lunchtime tutorial session on 2D-GC on Day 1. There will be live Q&A for the morning sessions and the tutorial. Attendance is free..*** On demand available after final airing until Oct. 23, 2021.***

This application note describes the measurement of ionic content in drinking water using the new HIC-ESP Ion Chromatograph to determine and minimize potential health risks.