Waters Corporation

Combining the benefits of the ACQUITY APC System with the ACQUITY UPLC Refractive Index (RI) Detector and the ACQUITY QDa Mass Detector yields laboratory efficiencies.

The selection of appropriate column chemistries to separate eighteen polymer additives are routinely monitored in extractables and leachables (E&L) workflows.

A flexible analytical system was used in conjunction with a well-defined informatics workflow to elucidate degradation markers in Li-Ion battery electrolytes.

Combining the APC System with WinGPC UniChrom™ software allows researchers to increase the peak capacity of their research.

Collaborative efforts at Virginia Tech University drive better materials through polymer innovation and additive manufacturing.

⦁ How to use the ACQUITY APC system with aggressive solvent compatible p-QSM technology to support gradient polymer elution chromatography (GPEC). ⦁ Selecting the appropriate detector for enhanced performance and insight.

⦁ How equipping LC with multi-detection technology enables achieving high quality, high-resolution, and rapid sample analysis. ⦁ Leverage LS and RI detectors and viscometer technologies to calculate absolute molecular weight, hydrodynamic radius, and structure of the materials.

⦁ Determine polymer properties such as molecular weight, dispersity, and branching/conformation. ⦁ How to differentiate molecular structure across the molecular weight distribution.

⦁ Reduce run time and solvent consumption by scaling both isocratic and gradient methods using the Alliance HPLC. ⦁ Utilization of the Waters Columns Calculator for scaling isocratic and gradient methods.

⦁ Develop a high performance and robust method for the analysis of formoterol, budesonide, and related compounds. ⦁ Show the straightforward method development capabilities of the ACQUITY™ Arc™ System in combination with Empower™ 3 Chromatographic Data System and S-Matrix Fusion QbD® Software.

⦁ Benefits of utilizing a custom library in the targeted analysis of migration samples. ⦁ Insight into how proposed workflow is used in identifying targeted and untargeted photoinitiators in migration studies.

-A detailed approach to data integrity aids regulatory compliance. -Advanced technology with automation capabilities can help reduce risks. -Data solutions include AI, software containers, cloud technology, and more.

Explore the analytical potential of the AQbD approach for achieving high-performance separations of formoterol, budesonide, and its related compounds.

The benefits of using QuanRecovery Vials for trace analysis of fatty acids in RPLC-MS based workflows.

In this application note, infliximab and trastuzumab were separated on a BioResolve SCX mAb Column, and their charge variant fractions were collected using a Waters Fraction Manager-Analytical (WFM-A).

The development and validation of a robust, quantitative method for the routine determination of a wide range of LC-amenable pesticides following QuEChERS (DisQuE dispersive sample preparation) procedure and LC-MS/MS

This document is designed to help the user performing intact and/or subunit protein analysis evaluate the performance or suitability of the instrument by undertaking a simple system check (SC) and running of QC standards.

The benefits of using QuanRecovery Vials for trace analysis of fatty acids in RPLC-MS based workflows.

Explore the analytical potential of the AQbD approach for achieving high-performance separations of formoterol, budesonide, and its related compounds.

In this application note, infliximab and trastuzumab were separated on a BioResolve SCX mAb Column, and their charge variant fractions were collected using a Waters Fraction Manager-Analytical (WFM-A).

The development and validation of a robust, quantitative method for the routine determination of a wide range of LC-amenable pesticides following QuEChERS (DisQuE dispersive sample preparation) procedure and LC-MS/MS

This document is designed to help the user performing intact and/or subunit protein analysis evaluate the performance or suitability of the instrument by undertaking a simple system check (SC) and running of QC standards.

Waters’ experts will illustrate the challenges of keeping computerized systems which are critical to regulatory compliance, under control. The CDRH Medical device group at FDA, are drafting an update for their guidance on computerized system validation. Primarily this is to promote a smarter risk-based approach to encourage the life science industry to adopt new technologies and automation opportunities, while remaining in compliance with regulations. How could a fresh look at available technology be used to innovate how such systems are deployed, allowing them to be regularly updated without creating a significant validation burden? Live: Thursday, Oct. 3, 2019 at 10am EDT | 9am CDT | 3pm BST | 4pm CEST On demand available after airing until Oct. 3, 2020 Register free

In this webcast, learn about the development of a fast and robust CQA monitoring method based on multi-attribute monitoring principles using a compact, compliance-ready LC-MS system. The presentation will demonstrate how the method can be easily transferred from development to manufacturing through commercial product lifecycle management. Live: Tuesday, Sept. 10, 2019 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST On demand available after airing until Sept. 10, 2020 Register free

Data Integrity has become a critical issue in the pharma industry as a result of increased regulatory scrutiny stemming from Data Integrity-related violations. This ebook provides insight on a variety of important topics within this space.

Ever wished you could improve detection of data manipulation and yet still reduce review time for chromatography data? Charlie Wakeham and Gary Cameron will explain how to leverage exception reporting tools to optimize your review process. Wednesday, Nov. 21, 2018 at 7:30am IST | 10am CST | 11am JST / On Demand: available until Nov. 21, 2019. Register free: http://www.chromatographyonline.com/lcgc/data_review

There is a struggle to adequately “document” audit trail review, which leads to the wider concern-how to adequately document any kind of quality review. What exactly does “signing a document” indicate? On Demand available until Jun. 1, 2018 Register Free: http://www.chromatographyonline.com/lcgc_w/data

Method transfer or method scaling across different LC instruments can be affected by both dwell volume and extra-column dispersion. Each characteristic will have a different effect on the chromatographic separation.