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The Application Notebook-03-01-2015
Special Issues
Determination of Phenolic Compounds in Virgin Olive Oil Using Comprehensive 2D-LC
March 01, 2015
Food and Beverage
0
This application note demonstrates how comprehensive 2D-LC can be used to resolve the complex mixture of hydrophilic phenols found in virgin olive oil and investigates differences in the phenol composition of several olive oils.
Controlled Reduction of Disulphide Bonds in Protein Therapeutics Using On-line EC–MS
March 01, 2015
Medical/Biological
0
Antec introduced the ROXY as an electrochemical reactor up-front MS. The electrochemically-assisted reduction of disulphide bonds followed by on-line mass spectrometric (MS) detection is presented.
Fast, Sensitive, and Simultaneous Analysis of Multiple Steroids in Human Plasma by UHPLC–MS–MS
March 01, 2015
Medical/Biological
0
Accurate steroid measurement is essential for the diagnosis of various disorders, for example in sexual differentiation or gonadal function.
Accurate Pain Management Analysis in Under 5 Min on RaptorTM Biphenyl Superficially Porous Particle LC Columns
March 01, 2015
Pharmaceutical/Drug Discovery
0
Pain management LC analyses can be difficult to optimize because of the limited selectivity of C18 and phenyl-hexyl phases.
Fast Analysis with SFC
March 01, 2015
Pharmaceutical/Drug Discovery
0
Supercritical fluid chromatography (SFC) has been used by scientists in laboratories and manufacturing facilities for several decades.
Characterization of a Monoclonal Antibody with Wyatt Technology’s MALS and RI Detectors and a Bio-Inert HPLC
March 01, 2015
Pharmaceutical/Drug Discovery
0
Multi-angle light scattering (MALS) represents a uniquely powerful technique to determine the absolute molar masses and sizes of proteins in solution. MALS detectors cover a wide detection range of sizes and masses and enable the characterization of protein molecules as monomers, dimers, or higher order aggregates.
Structure-Molecular Weight Relationships of Synthetic Polymers
March 01, 2015
Polymer
0
The physical properties and behaviour of polymers depends strongly on the properties of the polymer molecules themselves
Antibody Drug Conjugate (ADC) Analysis with SEC–MALS
March 01, 2015
Pharmaceutical/Drug Discovery
0
There has been a significant resurgence in the development of antibody-drug conjugates (ADC) as target-directed therapeutic agents for cancer treatment.