January/February 2026

Click here to access the LCGC International January/February 2026 Europe PDF in an interactive format.

A new version of United States Pharmacopeia (USP) <41> Balances becomes effective in February 2026. This installment of “Questions of Quality” explores the impact of the changes this brings, along with developments in the Japanese and European Pharmacopoeias.

The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy (Pittcon) has served as a major international meeting for analytical scientists across academia, industry, and government laboratories for more than 75 years. Pittcon 2026 will take place March 7–11, 2026, at the Henry B. González Convention Center in San Antonio, Texas, under the conference theme The Scientific Frontier.

In this installment of “LC Troubleshooting,” we take a close look at how the commonly used “flow-through needle” sampler works, discuss how and where leaks can develop, and solutions to the problems when they do occur.

Bob Pirok discusses the use of R², adjusted R², and F-tests to pick the right SEC calibration curve polynomial to avoid overfitting.

LCGC International salutes Jack Henion and Bob W.J. Pirok, winners of the 19th annual LCGC Lifetime Achievement and Emerging Leader in Chromatography Awards, respectively.

Combining silicon micro-nanofabrication technology to create perfectly ordered separation beds on a silicon chip, such as micro-pillar array columns (µPACs), is a powerful innovation in liquid chromatography. This article discusses the numerous possibilities of micro-nanofabrication in the future of analytical chemistry in life science, covering sample preparation, separation science, and detection technologies.