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LCGC North America-01-01-2014

LCGC North America

Peaks of Interest

January 14, 2014

Departments

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The Australian Patent Office has granted a patent related to W. R. Grace & Company's (Columbia, Maryland) Reveleris flash chromatography system.

Optimizing LC–MS and LC–MS-MS Methods

January 14, 2014

The Essentials

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Secondary parameters in the interface and mass analyzer can have a major impact on sensitivity and reproducibility. Here, we examine how and when to consider optimizing these parameters through a study of the working principles of LC–MS analysis.

Strategies for the Detection and Elimination of Matrix Effects in Quantitative LC–MS Analysis

January 14, 2014

Peer-Reviewed Article

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We assessed a simple method based on recovery for the detection of matrix effects and two alternative methods for the rectification of matrix effects in LC–MS: standard addition and the coeluting internal standard method.

Vol 32 No 1 LCGC North America January 2014 Regular Issue PDF

January 01, 2014

Issue PDF

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Click the title above to open the LCGC North America January 2014 regular issue, Vol 32 No 1, in an interactive PDF format.