LCGC North America-07-01-2003

John Dolan discusses the causes of peak tailing, how to measure it, preventive measures, and why newer column types are less prone to tailing problems.

This column is the first installment in a two-part series reviewing ICH and FDA impurity method validation guidelines.

This article focuses on the initial development of an LC–MS method to screen for cyanotoxins at low parts-per-billion levels.

John Hinshaw writes about the role that the American Society for Testing and Materials International plays in chromatography standardization.

The guest authors describe capillary columns for ultrahigh pressure liquid chromatography.