March 2023 | LCGC North America

Essentials of LC Troubleshooting, Part II, Continued: More Misbehaving Retention Times

March 01, 2023

Column: LC Troubleshooting

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When can analyte retention deviate from what is expected or normal? We explain three subtle causes.

Practical Understanding of Partition Coefficients

March 01, 2023

Column: Sample Prep Perspectives

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On a fundamental level, equilibrium and diffusion define chemical separations. Practical applications of partition coefficients to chromatographic sample preparation illustrate this point.

How Chemistry Determines Separations: Influence of Selectivity on Resolution

March 01, 2023

Column: GC Connections

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Understanding the relationship between selectivity and retention is key to realizing excellent gas chromatographic separations.

Analyzing Per- and Polyfluoroalkyl Substances (PFAS) in Foods

March 01, 2023

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As our knowledge about PFAS in food continues to develop, and regulations evolve, we must continue to refine our analytical methods.

Efforts to Increase Diversity and Equity in Introductory Chemistry

March 01, 2023

Columns

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Increasing inclusivity and equity in chemistry will require a positive instructor mindset, as well as invention, exploration, and trials.

Revisiting the Fundamentals of Untargeted Data Analysis with Comprehensive Two-Dimensional Gas Chromatography (GC×GC): With Great Peak Capacity, There Must Also Come Great Responsibility

March 01, 2023

Peer-Reviewed Article

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Two-dimensional gas chromatography (GC×GC) and chemometrics are leading the way in new strategies on multivariate data analysis. Using GC×GC in untargeted analysis reveals how far the technique has advanced the field of separation science.