LCGC Europe
This review provides an updated overview of the theory behind the success of SPP technology, trends, benefits, and limitations. It also summarizes the latest developments of sub-2-?m SPPs and instrumental constraints associated with their use.
LCGC North America
This fast, sensitive method provides accurate quantitation.
LCGC Europe
UV detectors are the most common LC detector, and perhaps the most reliable ones. But they are not without problems.
LCGC Asia Pacific
Some attributes of large molecules make them behave differently from small molecules in reversed-phase separations.
LCGC North America
What brought this scientist to where he is? And where he is going next?
LCGC Asia Pacific
Click the title above to open the LCGC Asia Pacific June 2014 regular issue, Vol 17, No 2, in an interactive PDF format.
LCGC Europe
Click the title above to open the LCGC Europe June 2014 regular issue, Vol 27 No 6, in an interactive PDF format.
LCGC North America
Click the title above to open the LCGC North America June 2014 regular issue, Vol 32 No 6, in an interactive PDF format.
The Application Notebook
Click the title above to open the LCGC North America June 2014 Application Notebook, Vol 32 No s6, in an interactive PDF format.
LCGC Europe eNews
Malvern Instruments Secures ?3 million from UK Government
10 common GC mistakes - are you guilty of making them?
The Column
Scientists at the University of Cambridge (Cambridge, UK) have reconstructed the early conditions of the Earth?s oceans to find that spontaneous chemical reactions could have generated the first biological molecules, before the evolution of organisms or the existence of enzymes.1 The study published in the journal Molecular Systems Biology presents data collected from liquid chromatography?triple quadrupole mass spectrometry (LC–QTOF–MS) suggesting that reactions central to our core metabolism could have spontaneously occurred.
It's just a silica support with a C18 bonded on, surely there can't be much difference between them? Wrong.
The Column
Over the last 30 years, the occurrence of head and neck cancer in Spain has been increasing, and now accounts for between 5–10% of malignant tumours diagnosed each year.1 In a new study published in the journal Chromatographia, solid-phase microextraction (SPME) with gas chromatography coupled to mass spectrometry (GC–MS) has been performed to identify two potential biomarkers of epidermoid laryngeal cancer, that could be used in non-invasive diagnostic testing.
LCGC Europe eNews
The latest newsletter from May 29.
Podcasts
E-Separation Solutions
Click here to view the complete E-Separation Solutions newsletter from May 27, 2014.
LCGC Asia Pacific eNews
Agilent Technologies (California, USA) is to collaborate with Seoul National University (Seoul, South Korea) to open a new research centre that will support the College of Pharmacy?s New Drug Development Centre.
The Column
The 2014 Emerging Leader in Chromatography Award was presented to Andrè de Villiers. Here we chart his career and accomplishments so far.
The Column
Incognito speculates on how 3D printing could change life in the laboratory.
The Column
This article presents a new method to evaluate the temperature shift observed in analytical temperature rising elution fractionation (ATREF). The evaluation is based on the dependence of the measured peak temperature as a function of heating rates. Application of the proposed method does not require any knowledge of the fluid circuit characteristics geometry and avoids the use of narrow preparative TREF standards. The results are found to be more accurate than the method that is usually applied.
The Column
Click the title above to open The Column May 22, 2014 North American issue, Volume 10, Number 9, in an interactive PDF format.
The Column
Click the title above to open The Column May 22, 2014 Europe & Asia issue, Volume 10, Number 9, in an interactive PDF format.
Anthony Gravell of Natural Resources Wales discusses the principles of passive sampling and the advantages of the technique over spot sampling when screening water samples for environmental contaminants.
E-Separation Solutions
James Frahill, Research Analyst, Pfizer Process Development Centre, spoke to LCGC about the role of the chromatographer in the pharmaceutical process development group at Pfizer.
The 41st International Symposium on High Performance Liquid Phase Separations and Related Techniques took place from 11?15 May 2014 in New Orleans, USA. One of the highlights of the conference was the poster presentation sessions, which were entered into a competition for the Agilent Technologies Best Poster Award.
E-Separation Solutions
A new study in the journal Heart suggests that high performance liquid chromatography tandem mass spectrometry (HPLC?MS?MS) could be performed as a standard screening tool to identify patients who do not take the anti-hypertensive medications as prescribed by their doctor. 1 The authors suggest that up to one in four patients is misdiagnosed as suffering with ?resistant hypertension?, when in fact the patient has not been taking their prescribed medications as advised.1
E-Separation Solutions
Many troubleshooting investigations in chromatography often don?t lead to a single causal factor. Often, the reason for problems or lack of method robustness are related to many small ?contributory factors? and this is particularly true of the problems associated with sample introduction in capillary Gas Chromatography.
