All News

An introduction from the guest editors of this special supplement from LCGC Europe focusing on some recent developments in pharmaceutical analysis.

This article shows how TD-GC-TOF-MS can be used to analyse the vapours released by strawberries.

Training courses in the practical applications of high-performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS) were held in Hangzhou on April 12, 2013.

Professor Boguslaw Buszewski, Chairman of ISC 2012 and President of EuSSS, CeGSS and the Polish Chemical Society, reveals the highlights of last year's illuminating programme.

The Column spoke to Dr Ailsa Benton - an "ice core" analytical scientist from the British Antarctic Survey (BAS) research team - about the role of chromatography in climate change.

A team of researchers from the Kobe University Graduate School of Medicine in Japan have developed a metabolomics-based approach to diagnose early-stage pancreatic cancer.1 The method uses gas chromatography coupled to mass spectrometry (GC?MS).

A new technique was developed based on liquid chromatography coupled with tandem mass spectrometry to analyze drugs that are not part of current immunoassay screening, specifically zolpidem, zopiclone, and zaleplone, or "z-drugs." This method allows for the simultaneous quantification of the z-drugs and all major benzodiazepines in human urine samples.

Soft ionization MS using GC–APCI-MS and GC–SMB-MS offers complementary identification power for the characterization of natural products, as illustrated by the identification of alkanes, sterols, long chain alcohols, and derivatized polar compounds in tobacco leaf extracts described here.

A new method is presented to evaluate the temperature shift observed in analytical temperature rising elution fractionation (ATREF).

Profiles of Peter W. Carr, the Lifetime Achievement in Chromatography award winner, and Davy Guillarme, the Emerging Leader in Chromatography winner

A new technique was developed based on liquid chromatography coupled with tandem mass spectrometry to analyze drugs that are not part of current immunoassay screening, specifically zolpidem, zopiclone, and zaleplone, or "z-drugs."

Short Courses

This month's installment of "Column Watch" comprises Part II of our yearly report on new products introduced at Pittcon. Gas chromatography columns, sample preparation products, and hardware, accessories, and small tabletop instruments mainly for sample preparation are covered.

Peaks of Interest

Euroanalysis 2013

Sometimes when changes are made to gradient conditions, the result isn't what was expected.

Here, degradation compounds similar to those formed in metabolic or environmental pathways were generated by adopting a photocatalytic process, quantified in environmental samples by liquid chromatography with multiple-stage mass spectrometry (LC–MSn) analysis using an orbital trap instrument with an electrospray interface, and then identified in indoor environments alongside parent compounds.

Click the title above to open the LCGC Europe May 2013 regular issue, Vol 26 No 5, in an interactive PDF format.

Click the title above to open the LCGC North America May 2013 regular issue, Vol 31 No 5, in an interactive PDF format.

Click the title above to open the July 2013 issue of Current Trends in Mass Spectrometry, Volume 11, Number 3, in an interactive PDF format.

Highly polar compounds ? such as small molecule pharmaceuticals, metabolites, and biomarkers ? can be challenging to separate using traditional reversed-phase separation methods. Several alternatives are available, including hydrophilic interaction liquid chromatography (HILIC), aqueous normal phase (ANP) chromatography, and HPLC using ion-exchange, polar-embedded, or polar-endcapped columns. So which option should you choose? Joseph Pesek of San Jos? State University explains the mechanisms, advantages, and disadvantages of these approaches.

LCGC is pleased to announce the additions of Emily Hilder and Davy Guillarme to its editorial advisory board.

Click here to view the full LCGC Europe E-newsletter from 29 April

The preservation of food in the home is a concern for all consumers. A group of researchers from INRA in Avignon, France, have conducted a study into tomato aroma with the aim of finding the optimum place for storage.

Scientists in Portugal have been investigating important molecular and biochemical changes that occur when grapes are growing to find out how they affect wine aroma.

Agilent Technologies (California, USA) has announced the establishment of the Asia Glycomics Education Center in South Korea, building on the recent collaboration with Chungham National University (Daejon, South Korea) through the university?s Graduate School of Analytical Science and Technology (GRAST).

Agilent Technologies (California, USA) has announced the establishment of the Asia Glycomics Education Center in South Korea, building on the recent collaboration with Chungham National University (Daejon, South Korea) through the university?s Graduate School of Analytical Science and Technology (GRAST).

Researchers from Queen?s University of Belfast (Belfast, Northern Ireland, UK) have shown that marine bacteria are able to efficiently biodegrade ionic liquids (ILs).