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Click the title above to open the LCGC Europe May 2014 Recent Developments in Sample Preparation Supplement, Vol 27 No s5, in an interactive PDF format.

New GC columns, SFC columns, and products for sample preparation, including small benchtop instruments

Part 2 of our yearly report on new products introduced at Pittcon. This instalment of "Column Watch" covers GC columns, SFC columns, and products for sample preparation including small benchtop instruments.

This month's "LC Troubleshooting" instalment looks at two reader-submitted questions regarding method calibration.

Event News

In this study, the quality-by-design principle is applied instead of trial-and-error in the development of a liquid chromatography (LC) method. A mixture of an active pharmaceutical ingredient and its 13 impurities was analyzed on a short narrow-bore column (50 mm ? 2.1 mm, packed with sub-2-?m particles) providing short analysis times. The performance of commercial modelling software for robustness testing was systematically compared to experimental measurements and design-of-experiment–based predictions.

This study presents results of gel permeation chromatography (GPC) and analytical temperature rising elution fractionation (TREF) of polyethylene in butylal (dibutoxymethane, a halogen-free solvent).

A multi-residue method has been developed and validated for the analysis of methylxanthines (caffeine and its metabolites) and cotinine in human plasma. The method has been successfully applied to the analysis of 500 samples from pregnant women in a clinical study.

The power of MS-MS analysis applied to GC analysis, including the instrumentation, experiment types, and application areas

Barry L. Karger, founding director of Northeastern University?s Barnett Institute of Chemical and Biological Analysis (Massachusetts, USA), has received the Arnold O. Beckman Award for Outstanding Scientific Achievements for his work in electrodriven separation techniques, sponsored by Sciex Separations, a division of AB Sciex (Massachusetts, USA).

Click here to view the complete E-Separation Solutions newsletter from May 1, 2014.

The latest newsletter from May 1.

Barry L. Karger, founding director of Northeastern University?s Barnett Institute of Chemical and Biological Analysis (Massachusetts, USA), has received the Arnold O. Beckman Award for Outstanding Scientific Achievements for his work in electrodriven separation techniques, sponsored by Sciex Separations, a division of AB Sciex (Massachusetts, USA).

Click the title above to open the LCGC Europe May 2014 regular issue, Vol 27 No 5, in an interactive PDF format.

Click the title above to open the LCGC North America May 2014 Advances in Food Analysis Supplement, Vol 32 No s5, in an interactive PDF format.

Click the title above to open the LCGC North America May 2014 regular issue, Vol 32 No 5, in an interactive PDF format.

Click the title above to open the May 2014 issue of Current Trends in Mass Spectrometry, Volume 12, Number 2, in an interactive PDF format.

Monoliths have received renewed attention in the past few years. Will they - or chip-based columns - ever compete with particle-based columns? In a short video interview, Dick Henry weighs in.

10 Ways to Break Your LC-MS

Check out this list of bad habits to avoid when using HPLC mobile phases.

Using proper procedures for capillary GC column storage and conditioning can have a major impact on column lifetime and the quality of results obtained. This "Tips and Tricks" instalment covers everything you wanted to know but were never told about proper GC column maintenance.

There are a few modifications which can be easily made, to both the HPLC system and column, which will achieve the desired goal of reduced analysis time. This article will provide some tips and tricks as well as detailing the theory behind the chromatography

A new approach for the analysis of water in solid pharmaceutical products using headspace gas chromatography (HSGC) with an ionic liquid (IL)-based open tubular capillary GC column has been proposed by scientists at the University of Texas at Arlington (Texas, USA). Published in the Journal of Pharmaceutical and Biomedical Analysis, the study states that the sensitivity of the method is 100 times that of the commonly used volumetric Karl Fischer Titration (KFT) (1).

A novel approach is described for the quantitation of three additives typically used in copper plating using a dual LC system with an ECD and a CAD.

This article addresses the contribution of thermal stability and column activity to BDE-209 breakdown and also describes an optimized method that resolves BDE-209 and other important congeners.

Incognito was met with initial disappointment after attending the Pittcon technical sessions, but was rescued from his gloom by the range of poster presentations on show that stimulated discussion and gave him some new insights (and new hope!) into developments in the field.

The 38th International Symposium on Capillary Chromatography (ISCC) and 11th GCXGC Symposium will be held at the Palazzo dei Congressi in Riva del Garda, Italy, from 18–23 May 2014.