All News

News All the news from January 2006 Opinion Zosimus questions whether we are being charged too much for our columns. Market Trends & Analysis Glenn Cudiamat provides a report on process analytical technology in the biotech and pharmaceutical industry. Evaluating analytical instrumentation using the Golf Score Card tool Timothy R. Baker, Steven H. Hoke II and L.M. Dobson ExTech, HTC-9 and Pittcon focus A useful update on these upcoming shows, together with a preview of some of the exhibitors' latest products. Q&A Ally Lewis from the University of York talks to The Column about his research into the analysis of organic compounds in the atmosphere. Supplies & services

For great advancements in understanding made by intuitive leaps to be successful, they must withstand rational scrutiny.

This postscript to the December 2005 installment "Early Petroleum Chromatographers" outlines the East–West controversy concerning the invention of chromatography.

The authors have developed a method of determining zeranol residues in bovine tissues without using toxic chemicals, organic solvents, and reagents in sample preparation and reversed-phase HPLC separation.

Size exclusion chromatography (SEC) coupled to light-scattering, viscometer and refractive index detectors is a common technique used for the characterization of polymers. In this article the solution conformations of two chimeric IgG3 antibodies were studied using this coupled triple detection technique. Conclusions indicate that the results allow hydrodynamic modeling of the antibody structures.

The effects of increased data demand coupled with the torrential data outflow of our instruments can overwhelm even the most IT-savvy.

Guest columnist Matt Przybyciel reviews the structure, behaviour and applications of both alkyl- and phenyl-fluorinated phases in HPLC. The author presents some guidelines on potential areas of application for alkyl and phenyl-fluorinated phases, in which conventional C8, C18 and phenyl phases might have insufficient selectivity or too strong retention.

Improvement of detection and quantification limits for LC methods is a result of taking advantage of all the tools you have at your disposal.

Thermo Electron Corporation (Waltham, Massachusetts) has recently announced the opening of a customer demonstration laboratory in Mumbai, India. The center will serve local pharmaceutical, petroleum/petrochemical, automobile, environmental, and agricultural market sectors and will be equipped with demonstration and training facilities.

Thermal conductivity detectors have been in use since before the beginning of gas chromatography. Essential for fixed-gas detection - no substitute has the same ease of use and stability - thermal conductivity detectors also are employed when the auxiliary or combustion gases required by flame ionization or other detectors are unsafe or impractical. Although they cannot match the sensitivity of ionization detectors, thermal conductivity detectors are the third most used detector, surpassed only by flame ionization and bench-top mass-spectrometry detectors. This month's installment of "GC Connections" takes a look at the operating principles and inner workings of the thermal conductivity detectors.

In this month's "Column Watch," Ron Majors answers HPLC column questions posed by readers and others.

An important prerequisite of a good sampling procedure for skin sebum is its reproducibility.

This article presents an overview of the work performed to define generic separation strategies and methods in chiral method development using capillary electrochromatography as a separation technique. Polysaccharide chiral stationary phases were found suitable for this purpose. Two separate strategies were defined, one for acidic and one for non-acidic substances. These strategies were evaluated and found applicable on structurally diverse molecules, showing their generic character.