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Two LC workshops will be held between 8?10 May at The Rubens at The Palace Hotel, London, UK. The courses are aimed at improving method development and providing solutions to common problems that occur with LC methods. The courses are brought by LC Resources and LCGC Europe, and sponsored by Hichrom.

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Pepper Computer Inc. has announced a new version of software for its Pepper Pad handheld media computer that brings users major new capabilities, such as integration with Yahoo's industry-leading Flickr photo-sharing community, while giving the Pad quicker performance.

The Column: February 2006

News All the news from February 2006 Opinion Zosimus voices his confusion ocer choosing silica and asks why so many brands are available. Market Trends & Analysis Glenn Cudiamat looks at the increasing demand for capillary electrophoresis systems particularly in the biotech and pharmaceutical industries. A new system for high-temperature gradient HPLC of polymers L.C. Heinz, T. Macko, A. Williams, S. O'Donohue and H. Pasch Selective extractions by molecularly imprinted polymers Christine Widstrand, Ecevit Yilmaz, Brian Boyd and Anthony Rees Country focus Find out about the latest developments in the UK and Benelux. Q&A Helmut Schulenberg-Schell, LC marketing manager of Agilent Technologies, talks to The Column about the company's latest LC and LC-MS product launches.

Agilent Technologies has introduced the 1200 Series liquid chromatography system as a successor to its 1100 Series LC. Liquid chromatography represents a $2 billion market and is one of the largest sources of revenue for Agilent's life science and chemical analysis business. Since introducing the 1100 Series instrument in 1995, Agilent has sold more than 400000 modules or 60000 LC systems. To ease the transition to the 1200 Series, the company has made the system reverse-compatible with the 1100 so that customers can combine new and existing modules and continue using existing methods without costly new method development, revalidation or retraining of operators. With more than 60 instrument modules, the system can be configured for all major LC applications, including a rapid-resolution format, preparative scale, standard, narrow, capillary, nanoflow and the company's chip-based liquid chromatography.

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Peaks of Interest

LECO Corporation (St. Joseph, Missouri) recently opened a global support center at its headquarters to serve domestic and international customers. The building will house its service, customer training, and consumables departments. An auditorium, training rooms, cafeteria, and restrooms have been designed exclusively for customers attending training classes. Up-to-date technology has been installed to ensure service and training needs for all customers are met quickly and efficiently.

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Liquid-liquid extraction (LLE) is among the most widely used sample preparation methods. In this month's installment of "Sample Prep Perspectives," Ron Majors discusses newer LLE approaches that offer significant advantages over classical methods. The miniaturization of LLE has resulted in solvent and time savings, improved automation possibilities, and faster sample preparation. The techniques of single-drop microextraction, extraction in levitated droplets, flow injection-, membrane-based-, and solid-supported extractions are reviewed. Often, these techniques use the same immiscible solvent pairs of conventional LLE.

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This article describes a software solution for automating the chromatographic method validation process starting from experimental planning, data acquisition and processing, through final report generation in a seamless manner. All experimental planning and calculations are accomplished within the chromatography data software and, thus, are structurally validated, secure, and audit trailed. Highlights of the software are provided, including benefits to the analyst. The analysis of important method validation characteristics such as linearity, accuracy, and precision is automated. These characteristics and their acceptance criteria can be captured in a method template, which adheres to the company's standard operating procedure. This template method can then be used repeatedly by other scientists in the organization, hence, eliminating the need to create a new experimental plan each time a new validation is conducted.