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A study aiming to identify fluorescent bioactive compounds in the coelomic fluid of earthworms, as well as to investigate their structural and functional characteristics for possible use in biomedical applications, utilized a variety of chromatographic techniques.

Gel permeation chromatography, three-dimensional excitation-emission matrix fluorescence spectroscopy, and UV-visible spectroscopy was utilized to assess road runoff passed through a filter filled with sludge from drinking water treatment plants to evaluate its capacity for removing dissolved organic matter (DOM).

A recent study described develops methods for synthesizing and quantifying metal-induced glycation products, particularly in French fries, with phytic acid as a natural chelating agent (NCA). LCGC International spoke to Makan Golizeh, corresponding author of the paper inspired by this research, about the study and the team’s use of liquid chromatography-tandem mass spectrometry (LC–MS/MS) in their research.

A team from the University of Geneva and Bayer AG present their findings on the on-off retention of oligonucleotides and the feasibility of separating them using very short columns.

A recent study used a liquid chromatography-drift tube ion mobility spectrometry-high resolution mass spectrometry (LC-DTIMS-HRMS) platform to contribute to characterizations of 175 per-and polyfluoroalkyl substances (PFAS) with authentic standards in a multidimensional manner.

Per- and polyfluoroalkyl substances (PFAS) often make headlines as health agencies worldwide work to regulate their use. While most restrictions focus on PFAS in drinking water, the primary exposure pathway, scientists are increasingly investigating alternative routes, such as dermal absorption from cosmetics, sunscreens, and other everyday products.

We recently published a three-part interview with Chris Reddy. Here, we provide the full text transcript of the conversation, which includes some additional insights not presented in the video interview.

The new benchtop encloser can be equipped with interchangeable onboard air filtration options to protect samples from contamination or reduce user exposure to harmful chemical gases.

Researchers have developed a method employing high performance liquid chromatography with ultraviolet detection (HPLC-UV) to determine vitamin D3 in food (even in the presence of vitamin D2, and with a specific focus on egg yolk) in a cost-effective and quantitative manner.

An investigation into fluoroelastomer watch bands has revealed high levels of perfluorohexanoic acid (PFHxA), a short-chain per- and polyfluoroalkyl substance (PFAS). LCGC International spoke to Professor Graham Peaslee from the University of Notre Dame about his team’s study using liquid chromatography tandem mass spectrometry (LC–MS/MS) and PFHxA's potential for dermal absorption, and the subsequent environmental and health impacts.

Waters Corporation recently announced two new columns to their MaxPeak Premier Reversed-Phase Column portfolio during the conference in Washington, DC.

In the second part of this edition of “Inside the Laboratory,” Christopher Reddy of Wood Hole Oceanographic Institution discusses why comprehensive two-dimensional gas chromatography is the optimal technique for investigating complex mixtures of organic chemicals in the environment.

“Forever chemicals” per- and polyfluoroalkyl substances (PFAS) have been found in smartwatch and fitness bands and analyzed using liquid chromatography tandem mass spectrometry (LC–MS/MS) and direct total oxidative precursor (dTOP) assay.

Researchers employed direct infusion/liquid chromatography-tandem mass spectrometry in their exploration of the potential of metabolomics to examine probable primary and secondary brain injury in severe traumatic brain injury.

In this edition of “Inside the Laboratory,” Christopher Reddy of Wood Hole Oceanographic Institution discusses his laboratory’s work investigating oil spills and uncovering dichlorodiphenyltrichloroethane (DDT) deposits on the ocean floor. This interview is part one of three of our conversation with Reddy.

Researchers from the University of Bordeaux (Villenave d'Ornon, France) report the development and validation of a rapid and quantitative analytical method measuring crown procyanidin concentration in red and white wines using ultra-high performance liquid chromatography (UHPLC) coupled with a ultra-high performance liquid chromatography (Q-TOF) mass spectrometer.

Here is some of the most popular content posted on LCGC International this week.

LCGC International sat down with Christopher “Chris” Reddy of Woods Hole Oceanographic Institution, whose research was the basis for a recently released documentary.

The American Chemical Society (ACS) released its new strategic plan, which reinforces the organization’s mission to improve lives through the power of chemistry.

Can a protein involved in delivering Vitamin D to target tissues have an altered serum profile in psoriasis patients with cardiovascular disease? Researchers used liquid chromatography (LC) to help find out.

LCGC International spoke to Michelle Klein from the Faculty of Chemistry of the University of Duisburg-Essen (Essen, Germany) about how, by using the green analytical chemistry tool Analytical GREEnness (AGREE) and the white analytical chemistry (WAC) framework, her team was able to conduct a comparative analysis of gas chromatography-tandem mass spectrometry (GC–MS/MS), liquid chromatography-tandem mass spectrometry (LC–MS/MS), and the yeast-cell-based reporter gene assay (A-YES).

Here is some of the most popular content posted on LCGC International this week.

The objective of this study was to investigate contamination by 32 plasticizers in olive oil throughout its production and packaging process. Separation and detection were carried out by gas chromatography tandem mass spectrometry (GC–MS/MS), without the need for pre-concentration steps.

Agilent Technologies recognized Professor Anders Bentien of Aarhus University, Professor Walter Gössler of the University of Graz, and Professor Gregory Offer of Imperial College London as their 2025 Solutions Innovation Research Award (SIRA) recipients.

The 43rd Annual Healthcare J.P. Morgan Healthcare Conference kicked off in San Francisco earlier this week. Here’s what top executives from Agilent, Bruker, and Waters, discussed during the event.

A recent study aimed to investigate the impact of lavender essential oil (LEO) and of its terpenic components on the properties of glioblastoma (GBM) cells in an in vitro model. The study demonstrated that LEO induces a proliferation slowdown and an impairment of cell migration of GBM cells besides reducing oxidative stress.

New research characterizes walnut milk residue according to its phenolic content and antioxidant and cytotoxic potential using ultrahigh-performance liquid chromatography–electrospray tandem mass spectrometry (UHPLC–ESI-MS/MS).

Here is some of the most popular content posted on LCGC International this week.