Podcasts

Following on our previous Dedicated Dialogue which discussed lab water contaminants and purification technologies, this Dedicated Dialogue will consider specific ways to handle and manage a lab water purification system and the product water from these systems in order to ensure consistent and reliable results.

Food contact materials contain low molecular weight additives and processing aids which can migrate into foods leading to trace levels of contamination. Food safety is ensured through regulations, comprising compositional controls and migration limits, which present a significant analytical challenge to the food industry to ensure compliance and demonstrate due diligence. Of the various analytical approaches, LC-MS/MS has proved to be an essential tool in monitoring migration of target compounds into foods, and more sophisticated approaches such as LC-high resolution MS (Orbitrap) are being increasingly used for untargeted analysis to monitor non-intentionally added substances. This podcast will provide an overview to this area, illustrated with various applications showing current approaches being employed.

This podcast will discuss the capabilities of modern ultra high resolution accurate mass (HRAM) spectrometry based approaches for comprehensive lipidome identification and quantitative analysis. Examples will be given of how this instrumentation can be used to overcome many of the identification challenges for lipidomics, the advantages of HRAM approaches over traditional triple quadrupole or high resolution based methods, and the biological questions that can be addressed.

Water is the most common reagent in the laboratory but it is the most misunderstood and is often taken for granted. Learn how specific contaminants can affect your chromatography system and results and understand how to optimize water purification technologies to meet your experimental needs.

Dr. Graeme McAlister of Thermo Fisher Scientific will discuss the advances in Orbitrap Tribrid Mass Spectrometry technology with the launch of the new Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer. Graeme will also touch on how these advances have impacted and will continue to impact proteomics with respect to quantitation, accuracy, throughput, etc.

The application of high resolution, accurate mass (HRAM) mass spectrometry coupled with multidimensional chromatographic separations, bioaffinity isolation techniques, and online sample preparation methods to detect, identify, and quantify emerging contaminants (including endocrine disruptors, pharmaceuticals, and surfactants) in wastewater and drinking water.The overarching goal of Lee’s research is to gain an increased understanding of how emerging contaminants are transported, transformed and induce deleterious effects within aquatic ecosystems.

Ultra high resolution, accurate mass (UHRAM) mass spectrometry, based on the Thermo ScientificTM OrbitrapTM technology, is a powerful new approach to high throughput screening and quantitation in complex sample matrices. To learn more about how UHRAM is used in the Million Metabolome Project, an ambitious milestone for Exposome Research, LCGC talked with Dean Jones of Emory University.Click to view the associated whitepaper

Ultra high resolution, accurate mass (UHRAM) mass spectrometry is a powerful new approach to high throughput screening and quantitation in complex sample matrices. To learn more about how UHRAM is used in metabolomics, LCGC talked with Jason Locasale, Assistant Professor in the Division of Nutritional Sciences at Cornell University.View the associated whitepaper.

An interview with Mark Hayes, a finalist for the 2012 FACSS-SciX Innovation Award. Part of the 2013 podcast series presented in collaboration with the Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), in connection with SciX 2013, the federation?s North American conference.

Well-known LCGC columnist Mike Swartz of Synomics Pharma Services discusses all that was new and noteworthy in the field of HPLC instrumentation at Pittcon 2010.