YMC America’s J Preston and Jeff Kakaley discuss the 5-in-1 functionality of YMC’s flagship chromatography system – the Contichrom® CUBE. They’ll explore using the instrument for different modes of chromatography, the added benefits of YMC resins, and how the CUBE can be used to scale up to YMC’s TWIN MCSGP systems.
Dr. Robin MacDonald shares a bit about her time working in the Broward Sheriff’s Office crime lab and how it has helped her in her role as Senior Product Manager at LabVantage to assist the team in developing software to support forensic organizations in their mission to deliver effective service to the judicial process.
The chemical and materials science industries are under increasingly public and regulatory scrutiny to improve their sustainability credentials. Join Ben MacCreath from Waters Corporation to discuss how their analytical solutions can help address some of the major concerns, including safety of consumer products.
Biotherapeutics such as monoclonal antibody-derived molecules as well as their impurity profiles are becoming more complex. That challenges the routinely applied analysis of high- and low-molecular weight impurities by size exclusion chromatography and UV-absorbance. Possible limitations of SEC-UV can be overcome by adding advanced detection technologies such as multiangle light scattering (MALS) and mass spectrometry (MS). This podcast will explain the different detection methods and the results they deliver. Special emphasis will be placed on the higher requirements for size exclusion columns and methods preceding advanced detection methods.
Introducing a new dimension in separations! The new HALO® 1.5 mm ID UHPLC columns from Advanced Materials Technology push the performance of UHPLC systems by delivering more sensitivity and 50% less solvent consumption than contemporary 2.1 mm ID columns. Additional benefits of moving to the new, robust 1.5 mm ID columns will be discussed including the ease of implementation commercial UHPLC instrumentation.
Per- and polyfluoroalkyl substances (PFAS) are of increasing concern. In October 2021, the U.S. Environmental Protection Agency (EPA) announced an action plan for addressing PFAS, including establishing maximum contaminant levels for drinking water. The vast presence and detrimental impact to human health and the environment of these analytically challenging compounds has led to focus on technique rigor necessary for sensitive, reproduceable and reliable data. In this podcast, Senior Application Scientist, Jamie Foss, addresses the differences between EPA methods 533 and 537.1, and how to overcome key LC-MS/MS technique challenges when performing analysis in accordance with these methods.
Keeping your instrument at peak performance levels is the best way to prevent loss of productivity due to unscheduled downtime. Proactive replacement of certain instrument components, tailoring instrument service to meet your specific lab’s needs and upgrading your instruments with the latest technology is the best way to cost-effectively manage your laboratory’s assets. Waters offers flexible service plans to help with the challenges of costly unplanned downtime.
Do you struggle with sample preparation? You are not alone! Sample preparation is often labeled as the no. 1 pain for scientists around the world. Scientists try to reduce this pain by settling for a sample preparation method or product that is less than ideal, causing even more pain further down the road. But imagine if you could eliminate some of that pain by simply choosing the right sample preparation product? In this podcast, we will help dissolve the myth that sample preparation pain is unavoidable by equipping you with proper selection recommendations and tips and tricks based on what matters to you most.
In the highly competitive beverage market, rapid and flexible processes and systems are vital for ensuring products meet the demands of the sector. As such, beverage processors must utilize portable, quick and intuitive testing solutions to ensure the production of high-quality beverages.
Filtering analytical samples and mobile phase solutions using the correct filtration device is an economical way to reduce instrument downtime, maintenance, and associated costs. Ensuing samples are free from particulate contamination will ensure the integrity of your instrument and columns, offering you more reliable and reproducible results. In this podcast you will learn more about the considerations that should be made when selecting the best analytical filtration device.
The latest Dr. Ehrenstorfer podcast sees LGC expert Dan Biggerstaff discuss the ever evolving topic of nitrosamines. Sharing his expertise, you'll learn about the complex but important topic of nitrosamine regulation, the challenges laboratories face when testing for nitrosamines and how to overcome these.
Finally, something that works! Find out how to get great testing results when quantifying cannabinoids in edibles. In this podcast, we will share simple extraction procedures to generate cleaner samples with the very best accuracy. If you are tired of clogging your LC columns and getting strange results, this podcast is for you.
In the final episode of this six-part podcast, Robert Moritz, a professor at the Institute for Systems Biology, discusses major challenges that still exist with liquid chromatography and mass spectrometry, liquid chromatography’s role in LC-MS proteomics, and where this field is headed in the next few years and beyond.
In the fifth episode of this six-part series, Bogdan Budnik, principal scientist at Harvard Center for Mass Spectrometry, discusses common challenges related to nano LCMS proteomics analysis of very diverse sample types, improvements in proteomics analysis, and how single-cell proteomics will impact the medical field.
Polymers for life-science applications have different attributes from traditional applications such as automotive and packaging. These attributes have their own set of challenges in the characterization requirements of such complex molecules. Multi-angle light scattering (MALS) technology provides a more insightful tool.
Aimed at GMP-regulated laboratories, this podcast discusses the regulatory and business drivers for digitizing analytical processes, how they go hand in hand, and some practical aspects on how to approach such a journey. The business benefits of improving laboratory efficiency by releasing product earlier, and technical controls to ensure regulatory compliance, should easily justify automation projects. It is crucial to automate now under your own timeline rather than be forced by regulatory citations.
Poor quality data can negatively impact a lab’s reputation and its bottom line. Jodi McDonald, President of Keystone Labs, applied her pharmaceutical GMP learnings to the challenges of cannabis testing. Gain from her experience as she shares tips to ensure the quality of cannabis from sample collection to analysis.
In the fourth episode of this six-part podcast, David Perlman, senior principal scientist and director of ultrasensitive proteomics at the Merck Exploratory Sciences Center, discusses where LC-MS proteomics has the largest impact, the need for single-cell proteomics, the promise single cells have on our day-to-day lives, and more.
In episode 3 of this six-part series, Karl Mechtler, head of the protein chemistry facility at the Research Institute of Molecular Pathology, Vienna, Austria, discusses the critical role of nano LC separation performance for reproducible and quantitative deep-dive proteomics analysis.
This episode will cover the progress towards a new AOAC method for metals in cannabis and the efforts taken toward reaching this goal. Helpful information for all cannabis labs interested in running metals will be shared, including our latest and greatest, ICP-MS Cannabis Analyzer and how it should be a player in your lab!
Biomolecules such as proteins, antibodies or viral vectors are becoming increasingly important therapeutics, as evidenced by clinical trials and ultimately drug approvals. But they are also significantly different from small molecules, which affects their HPLC analysis. We explain the differences and what that means for the HPLC conditions and modes used to analyze biomolecules.
