Podcasts

Potency testing in cannabis, hemp, and cannabinoid products is required in every region where the use and production of these products is permitted by law. Although ostensibly a simple HPLC testing method, it can be fraught with potential pitfalls. These include poor extraction efficiency, poor methodology, and outcome bias from lab to lab. In this episode, we will examine these issues and discuss the utility of mass spectrometry as an alternative to address the shortcomings of HPLC.

Alexander Boychenko, Product Marketing Manager at Thermo Fisher Scientific focused on low-flow LC technologies provides insights into the benefits of the state-of-the-art nano-, capillary- and micro-flow UHPLC system hyphenation with MS.

The need for enhanced product quality of biomolecules has led to a higher-level of characterization of different critical quality attributes. Size exclusion chromatography (SEC) has been widely used as a technique to provide size and purity. SEC coupled with multi-angle light scattering (MALS) can determine molecular weight (MW) and size (or radius of gyration, Rg) of complex samples. Dr. Wei Lu, Ph.D. and Philip Hoang from Tosoh Bioscience discuss how SEC-MALS as an analytical method can be optimized and applied to a wide range of applications including oligonucleotides, monoclonal antibodies, and virus-like particles.

This podcast will examine peak deconvolution with photodiode array detectors and how a unique software function can separate peaks that are not resolved on-column, yielding better detection results and minimizing method development and analysis time. The podcast will explore the development of this tool with a leading pharmaceutical company and provide examples of how it can have an impact across a wide range of disciplines in the pharma/biopharma arena, from development to production.

Recent life science technologies incorporate polymers and biopolymers as key component of their drug products. Polymers play essential roles in controlled drug elution as well as target drug delivery, therefore advanced analytical solutions are required to properly assess the safety and efficacy of these new life science technologies. Join-us to learn more about the advanced analytical solutions for life science technologies.

Go beyond the hype of digital transformation and learn its true promise. With advanced analytics in your pharma labs, you can transform all your data into actionable scientific and business insights that lead to better outcomes. LabVantage Solutions is working with pharmaceutical companies worldwide to integrate their labs with their enterprise digital ecosystems. Find out how LabVantage’s informatics platform, complete with AI-powered, self-service analytics, is making a difference across the pharmaceutical industry.

Ionization Labs, through their Cann-ID potency testing solution has opened up market access to high level chemical analysis tools that have historically been available only to highly trained users. Hear from the Ionization Labs Co- Founders on what sets their solution Cann-ID apart and why every cannabis / hemp operation should be utilizing it.

Lab scientists are constantly faced with challenges caused by aging technology including longer run times, expensive repairs and less sensitivity of their samples. As instruments approach end of life, accessing trained professionals to repair older technology also becomes more difficult and costly. In this podcast, Heather Rennie, Senior Manager, Global Services, from Waters Corporation will discuss the benefits of protecting instrumentation by including a service coverage support package at the time of purchase.

Hear from those educating the next generation of cannabis testing lab scientists. What are the challenges of hiring highly qualified cannabis analysts in the current labor market? Learn about the range of skill sets cannabis laboratory staff will need to be successful.

As one of the most promising in-vivo gene delivery vectors, adeno-associated virus (AAV) has been widely used in various gene therapy products. In order to ensure the safety and efficacy of these AAV-based gene therapy products, it is crucial to understand and measure their critical quality attributes (CQAs) throughout the development cycle. In this podcast, we will discuss how to apply a well-established bio-therapeutics characterization tool, SEC-MALS (size-exclusion chromatography combined with multi-angle light scattering and other online concentration detectors), for quantifying AAV CQAs. This SEC-MALS method has been recognized and demonstrated as a robust, sensitive, and automated assay for AAV development platform and production release testing.

- Ultrapure water with a constant high quality is important because the presence of impurities and contaminants occurs to wrong results - Arium® systems meet and exceed the standards to guarantee reproducible results - Arium® Ultrapure water systems are especially designed for analytical applications like ICP-MS and HPLC

Part 1 of the Pharmaceutical Roots content series from LGC Mikromol investigates the natural origins of aspirin, and offers a deeper dive into its uses, risks, and mechanisms of action.

There is an increasing focus on capturing utilization data from instruments to improve overall lab operations. Utilization data without context such as service history, instrument information and maintenance strategy has limited value. Contextualizing utilization data improves quality of the business decisions relating to the asset lifecycle.