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Pesticide Residue Analysis in Food: Advances, Challenges, and Case Studies

Tackling the Heat: Overcoming Matrix Challenges in Pesticide Residue Analysis of Chili Powder Using LC–MS/MS
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A recent study examined a new method to optimize raisin production by demonstrating how pretreating grapes with extra-virgin olive oil (EVOO) before dehydration can significantly improve the retention of beneficial phenolic compounds during raisin production and storage.

Trap focusing offers a powerful solution to common challenges in headspace (HS) and solid-phase microextraction–gas chromatography (SPME–GC) analysis of foodstuffs, including poor peak shape, limited sensitivity, and restricted dynamic range. This article explores how automated cryogen-free focusing, combined with multi-step enrichment and re-collection capabilities, can improve the detection and quantitation of both aroma-active compounds and trace-level contaminants. Using real-world examples, including flavor profiling of cola and garlic, and quantitation of ethylene oxide and epichlorohydrin in spices, enhanced chromatographic performance, greater confidence in compound identification, and lower detection limits than traditional workflows such as direct SPME or QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) are demonstrated.

A recent study demonstrated how analytical techniques can be used to differentiate between different types of whiskey.

The approach describes a new untargeted, trapped-headspace (THS)-GC-QMS-IMS setup for an exhaustive VOC analysis of complex food, beverage, and flavor products, and allows the classification of mango cultivars in combination with chemometric data evaluation.

We highlight how chromatography is being used to analyze Irish whiskeys.

Researchers at the Dalian Institute of Chemical Physics at the Chinese Academy of Sciences, have developed a rapid FastGC-PICI-TOFMS method that detects the carcinogenic compound ethyl carbamate in Chinese liquor in under four minutes.

Best of the Week: Call for New Technology Submissions, Decoding Plant Stress Responses, Quantifying Cocoa Alkaloids
In this article, you’ll find some of the top content that was published on LCGC this week, including calls for new chromatography technologies and interviews with rising stars in the field.

In this article, you’ll find some of the top content that was published on LCGC this week, including details on the recent merger between Waters Corporation and BD Biosciences.

In this article, you’ll find some of the top content that was published on LCGC this week, including a technical article on food flavor and an interview with the president of Shimadzu Europa.

The panel concludes by envisioning the future of PFAS research and analysis.

The conversation turns to collaboration—highlighting the value of cross-sector partnerships in advancing PFAS science, securing funding, and fostering scientific progress.

In a new study, researchers used GC–MS and LC–MS were used to detect composition fraud in food supplement creation.

A new dried spot-based technique involving untargeted liquid chromatography coupled with high-resolution mass spectrometry was testing for characterizing foodstuffs.

Panelists discuss the creation and use of PFAS libraries and databases, stressing the need for comprehensive, up-to-date resources to support accurate compound identification.

Scientists examine the role of non-targeted analysis in discovering unknown PFAS, and how automation and data processing tools are accelerating this work.

Analysis of VOCs is essential to maintain product consistency by detecting whether growing, refining, and production processes have an impact on the smell and taste of the product or whether a product has been tampered with.

This article explores the technological advancements in HPLC that enhance its role in analyzing PFAS in food, including innovations in column technology, detection systems, and sample preparation techniques.

The panel examines how evolving global regulations are shaping approaches to PFAS analysis, while also highlighting how ongoing research enhances our understanding of these contaminants and informs regulatory decision-making.

In this episode the panelists unpack how laboratories can reduce background contamination and improve sensitivity through rigorous method optimization and instrument handling.

The panelists discuss the challenges of analyzing short-chain PFAS and highlights how emerging techniques like ion mobility offer promising solutions.

In this episode the panelists explore emerging analytical techniques that are enhancing PFAS quantification.

This article describes the analytical challenges of chemical exposomics in food safety. The need for high-throughput, multi-platform approaches—such as LC–HRMS and GC–HRMS with IMS—to capture the full spectrum of potential contaminants in our food supply is emphasized.

Monitoring the quality of essential oils is vital for protecting consumer health. Researchers recently combined gas chromatography and mass spectrometry approaches to gather data on mandarin essential oils.

Here is some of the most-read content posted on LCGC International this week.

Grape pomace, a byproduct of the winery industry, holds various phenolic compounds within it. Scientists used liquid chromatography-based techniques to harvest these potentially beneficial components.








