Developments in HPLC Column Packing Design

Column packing materials continue to evolve as user needs for highthroughput, high-resolution and high-sensitivity HPLC analyses drive further developments. In this introductory article to this supplement, Ron Majors covers basic column packing morphology and particle design and compares and contrasts modern HPLC columns. Some applications of modern HPLC columns are provided. Future directions in packing developments are predicted.