Recent Advances in Ultrahigh-Pressure Liquid Chromatography

Ultrahigh-pressure liquid chromatography (UHPLC) is a technique that is experiencing continued growth due to the benefits in separation power and speed of analysis over traditional HPLC. We attempt here to give an overview of some of the advances that have occurred in UHPLC since 2003, from the standpoint of both fundamental research and the introduction of commercially-available technology.