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Three Day Virtual Symposium: Separation Science- The State of The Art
The Global Chemical Industries Summit
The Power of CE-MS in Biotherapeutics Characterization
Capillary Gas Chromatography: Getting the Best Separation Without Turning (Too Many) Wrenches
The Hidden Factory in Your Laboratory?

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Liquid Chromatography (LC/HPLC)
Gas Chromatography (GC)
Sample Preparation
Mass Spectrometry
Pharmaceutical Analysis
Environmental Analysis
Food and Beverage Analysis

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A Four-Column Approach to Developing Stability-Indicating HPLC Methods

June 1, 2002

Jeffrey R. Mazzeo, Eric S. Grumbach, Steven Collier

LCGC North America

LCGC North America, LCGC North America-06-01-2002, Volume 20, Issue 6

This article describes a method development approach that uses different packing materials and mobile-phase pH levels to optimize the chromatographic separation of degradation products from active ingredients.