A Four-Column Approach to Developing Stability-Indicating HPLC Methods

Mazzeo,Jeffrey;Grumbach,Eric;Collier,Steven;

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High-Throughput Analysis of Volatile Impurities in Sustainable Packaging using SIFT-MSAutomated Sample Prep in Regulated and Nonregulated Labs Just Got EasierWhat is Chemical Composition Distribution in Polyolefins, and Why Should It Be Part of Your HT GPC Analysis?How Well Do You Pipette?Probe Electrospray Ionization-Mass Spectrometry and Isotope Dilution Approaches

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A Four-Column Approach to Developing Stability-Indicating HPLC Methods

Published on: June 1, 2002

Jeffrey R. Mazzeo, Eric S. Grumbach, Steven Collier

LCGC North America

LCGC North America, LCGC North America-06-01-2002, Volume 20, Issue 6

This article describes a method development approach that uses different packing materials and mobile-phase pH levels to optimize the chromatographic separation of degradation products from active ingredients.