
At ISC 2026, a tailored C4 stationary phase resolved over 30 of 64 possible siRNA diastereomers, aiding characterization of oligonucleotide conjugates.
This month's guest authors review the application of solid-phase microextraction (SPME) to the analysis of drugs in human plasma discussing important factors in the optimization of extraction efficiency. The column concludes with a discussion of method validation issues.
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