Retention Time Changes

A study conducted at Henan University of Science and Technology (Luoyang, China).aimed to characterize the pharmacokinetic profiles of milbemycin oxime in Pekingese dogs following a single oral (PO) and intravenous (IV) dose. Blood samples were collected at various time points, with milbemycin oxime concentrations measured using a validated high performance liquid chromatography (HPLC) method with ultraviolet (UV) detection.

The aim of the study was to illustrate the efficiency of Milli-Q® water purification systems in eliminating pesticides from tap water, and thereby producing and delivering reliable and consistent-quality ultrapure water suitable for pesticides analysis

Research on plastics in aquatic environments is well-established, but little is known about their presence, pathways, and effects in soil ecosystems. The iMulch project aims to address this need as well as the growing concern of plastic pollution in soils. Focusing on developing and validating methods to detect micro- and macroplastics in soils and drainage waters, with an emphasis on how drainage water impacts municipal wastewater treatment, a key aspect of the study is analyzing plastic emissions from agricultural mulch films. We spoke to Carmen Wolf of the Institute for Environment and Energy, Technology and Analytics e.V. (IUTA) in Duisburg, Germany, corresponding author of a recent paper on the project, about the investigations involved and how separation science was used in their experimentation.

The researchers explored ways to simplify retention time calculation across LC–MS and various other chromatographic methods.