Application Notes: General

Modified nucleosides, either natural or synthetic, often provide RNA with distinctive properties useful in diagnostics or therapeutics.

The PRP–C18 isolates structurally diverse pharmaceutical compounds in under 6 minutes using basic solutions.

Ion pairing agent aided separation of oligonucleotides from their potential failure sequences highlighting the Hamilton family of reversed-phase HPLC columns.

The rugged C18 column design provides large loading capacities and great reliability required for repeated use in manufacturing production lines.

Common hormone steroids are isolated based on their lipophilicity valve.

Detection of eight metabolites of benzodiazepines are achieved in under 10 minutes. Both glucuronide forms and parent compounds are observed by UV HPLC.

This application note shows the LC–MS analysis of multiresidue pesticides. Quantification, linearity, and matrix recovery limits are shown for the pesticide compounds.

Good retention and peak shape for Atorvastatin is observed on Quasar AQ phase in this application.

The separation and identification of 16 common drug substances is possible in the field using a combination of a portable GC/MS in under 10 min.

The Quasar SPP C18 HPLC phase offers high efficiency separation of the anti-inflammatory drug, naproxen.

Fentanyl, acetyl fentanyl, carfentanil, and heroin were collected and identified using CME syringes with our portable GC–MS in drug screening scenarios.

This application looks at the differences in chromatography between the Quasar C18 and AQ phase chemistries for the analysis prednisolone, prednisone, and cortisone.

This technique achieves highly reproducible and fast analysis of organochlorine pesticides in water by coupling automation with the use of a disperser solvent.

The Eclipse Neutrino, a premier monomer analyzer process gas chromatograph, couples MSD, PDHID, and FID detectors to characterize an extremely broad range of analytes from fixed gases to C5+. Quickly detecting ppm-ppb levels of impurities and catalyst poisons.

Robust and accurate primary sequence confirmation and monitoring of post-translational modifications of the SARS-CoV-2 spike protein using the BioAccord LC–MS system.

Eliminate the need for column conditioning, improve recovery, and improve repeatability by minimizing non-specific oligonucleotide interactions with metal surfaces.