Application Notes: General

This application note describes the company’s range of oligonucleotide columns and oligonucleotide standards.

This application note demonstrates the suitability of the company’s stationary phases to separate deprotected RNA and DNA oligonucleotides of different sizes.

A method using the company’s system to purify long-and short-term oligonucleotides is described.

This application note demonstrates direct ion-pair reversed-phase online desalting using 2D -LC for the analysis of oligonucleotides.

Polymeric strong anion exchange methods such as PL SAX are suitable for anion exchange and purification of oligonucleotides. At elevated temperatures, enhanced mass transfer increases the resolution for larger oligonucleotides. Working at higher PH values enables resolution of phosphodiester and phosphothioate forms of the oligonucleotide.

IONICON PTR-TOF real-time breath gas analyzers are deployed for finding a quick, non-invasive test to identify a SARS-CoV-2 infection in exhaled breath.

Key bourbon odorants with flavor dilution factor 201 found by solventless extraction and GC–MS/O-Aroma Dilution Analysis. Data analysis and AEDA-like reporting is shown.

GC/MS system capabilities can be expanded using versatile technology. A new multi-mode pyrolyzer addresses analytical challenges and increases efficiency.

This application describes the purification of paracetamol from a crude sample in early-stage drug discovery. Outstanding purity (>99%) and recovery (>95%) are achieved.

This application note describes the improved identification of pharmaceutical low-level impurities when using SFC and UHPLC as orthogonal separation modes.

Dans cette note d’application vous découvrirez le QTof 6545XT et le logiciel BioConfirm 10.0 pour l’identification et la quantification des modifications post traductionnelles.

Cette brochure explique comment Agilent prend en charge l'ensemble du flux de travail des glycans de la préparation des échantillons à l'analyse LC, FLD, MS, et CE.

Téléchargez cette application pour connaître notre solution à la caractérisation de protéine native complexe non covalent par HPLC SEC–MS : Application aux mAb, ADC, et complexes protéiques.

Ce compendium couvre les techniques analytiques utilisées dans l’identification et la quantification des attributs de qualité critiques sur l’exemple de l’anticorps monoclonal NIST.

Producing chromatographic media with two-photon polymerization printing Nanochannel electrophoresis in plastics Innovations in portable LC instruments; 2D-LC; chromatography for cell therapies

This application demonstrates the efficacy of this chromatographic technique for a fast orthogonal analysis to evaluate mAb ADCC activity.

Learn more about our HPLC-QTOF solution for the identification and quantification of post-translational changes for the development of therapeutic antibodies.

In this applications resource you'll know how Agilent supports your entire released glycan workflow from sample preparation to LC-FLD–MS and CE analysis.

Download this educational resource which covers applications for characterizing critical quality attributes

Discover our latest application note on native protein analysis by steric exclusion chromatography and high-resolution mass spectrometry.

Low valency high-molecular weight (HMW) impurities and low-molecular weight (LMW) impurities are analyzed on a 450 Å Protein BEH SEC column for several AAV serotypes.

The relative level of AAV8 without single-stranded DNA can be assessed using strong anion-exchange chromatography, and separations are shown for several AAV serotypes.