Application Notes

By identifying maturation tracers and molecules commonly responsible for taste defects, gas chromatography–mass spectrometry (GC–MS) augments expert opinion with objective and quantitative information. When using a solid phase micro extraction (SPME) method, GC–MS requires very small sample sizes and a minimum of sample preparation while providing rapid analysis of target molecules. GC–MS can provide an automated technique with repeatable results for detecting all of these compounds.

Saccharides are fundamental substances that express various bioactivities and may exist independently or form complexes with proteins or lipids.

Blueberries are extracted into acidified methanol and analyzed for anthocyanins with a methanol/formic acid gradient via UHPLC/MS; four different Agilent ZORBAX RRHD stationary phases are quickly evaluated.

Resistive glass tubes and plates are designed to guide ions by generating a uniform electric field. PHOTONIS resistive glass products are composed of a proprietary lead silicate glass that has been specially processed to create a resistive layer at the surface. The resistivity can be varied over several orders of magnitude to suit the specific application.

Basic compounds often require basic additives in the modifier to improve peak shape and resolution in SFC (1). These additives can be difficult to remove post-purification (2).

Since September 2008, 294 000 infants and young children suffered urinary problems as a result of the contamination of melamine in infant milk powder and were hospitalized. This hospitalization was required to treat the symptoms caused by the ingestion of melamine contaminated infant formula and related dairy products. Previously in 2007, pet food, animal feed wheat gluten and other protein-based foods were found to contain residues of melamine and its degradation product cyanuric acid.

Forensic laboratories face a daunting task to identify trace amounts of controlled substances in small samples of seized evidence. Unambiguous identification is required to meet the stiff challenge that is sure to be raised in the courtroom. Positive proof is especially difficult to establish if the controlled substance is hidden in a complex food matrix with a high content of sugars, fats, fatty acids, proteins and alkaloids.

Penicillins are regulated substances in food for human consumption. The minimum residue limits range from 1 ng/g to as high as 50 ng/g depending on the compound. Because of the complexity of food matrices measuring the level of contaminants requires a total solution composed of sample extraction, sample clean-up, chromatographic separation and detection. In this paper, a solid-phase extraction method with a high performance liquid chromatography tandem mass spectrometry method (HPLC–MS–MS) is shown for the simultaneous determination of six antibiotic residues.

EPA Method 8260 is used to determine volatile organic compounds (VOC's) in a variety of matrices including ground and surface waters. This method is commonly used in environmental laboratories where gas chromatography (GC), mass spectrometry (MS) and purge and trap (P&T) technology are used for the analysis and subsequent detection of VOC's.

The CUSTODIONâ„¢ solid phase microextraction (SPME) syringe was used to rapidly sample and concentrate volatile organic compounds (VOCs) from water in 5 s. The VOCs were analyzed quickly and reliably in approximately 70 s using the GUARDIONâ„¢ -7 portable capillary gas chromatograph toroidal ion trap mass spectrometer (GC-TMS).