Using a mass spectrometer as a gas chromatography (GC) detector has many advantages for compound identification and quantification, but there is another less-known benefit: speeding up analyses by using the mass spectrometry (MS) vacuum to lower pressure within the column. This technique, also known as “vacuum‑outlet GC” or “low-pressure GC–MS” (LPGC–MS), can provide significant gains for fast GC–MS.
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We show the separation of tacrolimus from its related substances following Ph. Eur. monograph 2244 using the Luna 3 µm C18(2) and Luna Omega µm.
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We report the separation of diazoxide and its related organic impurities using a Kinetex ™2.6 µm biphenyl column according to the USP monograph for diazoxide.
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This step-by-step selectivity guide is an overview of the reversed-phase HPLC/UHPLC options available to you, highlighting the differences between the columns.
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LC–UV assay and organic impurities for paliperidone drug substance based on USP monograph where a L1 (C18) column with 100 x 4.6 mm, 3 µm dimensions was used
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LC–MS/MS method to separate furosemide and its metabolite using three different columns: Kinetex 2.6 µm Biphenyl, Luna Omega 1.6 µm C18, and Luna Omega 1.6 µm Polar C18
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Luna Omega 1.6µm, 3µm, and 5µm HPLC/UHPLC columns culminate 20 years of technological prowess, advancements, and innovation.
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Easily determine the allowable adjustments that can be made to European Pharmacopoeia (EP) methods and find the right column for your method.
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Quickly view allowable adjustments outlined by the United States Pharmacopeia (USP) and select the proper Phenomenex column for your monograph using this simple guide.
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Analysis of ABN7 test mix used to assess scalability for Luna Omega C18 columns across a range of particle sizes (1.6 µm, 3 µm, and 5 µm) in three different dimensions.
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Improve United States Pharmacopeia (USP) method performance with allowable adjustments
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This application note details two LC–MS/MS methods for the analysis of 30 analytes from veterinary drugs in milk.
To monitor FcR receptor binding, a recombinant FcγRIIIa-ligand has been commercialized into TSKgel FcR-IIIA high-performance affinity chromatography (AFC) columns that separate antibodies based on affinity differences to FcγRIIIa.
