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Multiple laboratories applied method EPA 537.1 and 533 for the extraction of PFAS in pristine non-potable water and source water assessment.

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Multiple laboratories applied method EPA 537.1 and 533 for the extraction of PFAS in pristine non-potable water and source water assessment.

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PFAS experts provide insight on workflow considerations on how to manage and prevent cross-contamination to ensure quality analysis.

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A comprehensive selection of applications for the determination of Persistent Organic Pollutants (POPs)

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FAQ on scope, workflow, timeline, requirements for the Fith Unregulated Contaminants Monitoring Rule (UMCR 5)

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Analysis of HFPO-DA in a multi-residue method along with 24 other common PFAS

Webcasts
Wednesday, September 14, 2022 Morning Session: 9am EDT | 6am PDT | 2pm BST| 3pm CEST Afternoon Session: 1pm EDT | 10am PDT | 6pm BST | 7pm CEST Are your analytical methods keeping up with the pace of new biotherapeutic drug modalities? Attend this symposium to ensure success!

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NIST mAb was analyzed using six different batches of 1.8 µm 200 Å dSEC-2 media packed with 150 mm length and 4.6 mm inner diameter columns.

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Method development using standard phosphate containing buffers with different percentages of Isopropanol for aggregate analysis of an antibody-drug conjugate, Kadcyla.

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The hydrophilic nature of the Biozen dSEC-2 stationary phase shows favorable aggregate profiles for forced degradation work under high salt conditions.

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Higher peak area for Biozen dSEC 2 column showing less adsorption occurring. Superior peak shape and recovery under USP mobile-phase conditions with Biozen dSEC 2 column.

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Robustness of guard and attached analytical column evaluated for efficiency of trastuzumab biosimilar Kanjinti at suitable loading masses of bovine serum albumin.

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Protein standards explored with known hydrodynamic radii, show how this can determine ideal size-exclusion conditions for optimal method performance using Biozen columns.

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In this application note, we demonstrate the utility of size-exclusion chromatography (SEC) for the detection of high-order structure of single-stranded DNA oligonucleotides.

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Size-exclusion method improvements by running at a lower flow rate for the aggregate analysis of NIST mAb using a Biozen dSEC-2 column

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This technical note demonstrates the characterization of subunits for three monoclonal antibodies, post digestion with IdeS, using the Biozen dSEC-2 size-exclusion column.


Webcasts
Tuesday, July 19th, 2022 Register today to expand your knowledge of LC column selection and method development for diverse pharmaceutical methods, and to learn how to optimize intermolecular interactions for sensitivity and resolution.

Webcasts
Wednesday, June 1st, 2022 at 2pm EDT|11am PDT|7pm BST|8pm CEST As more PFAS compounds are discovered and more complex matrices are tested, both regulated and unregulated analytical methods will need to adapt. This webinar will show the benefits of alternative workflows, such as high-resolution mass spectrometry and other screening techniques, to ensure the proper identification of PFAS compounds while providing quantitative results. It will also address the modification of the stationary phases of varying surface chemistry and eluents of varying polarity, which causes the sorption-elution characteristics of different classes of PFAS compounds to be altered.

Executive Summary

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Guide to PFAS testing in food and food contact materials that require more extensive analytical preparation techniques, compared to PFAS testing of drinking water

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Complete selection of applications for pesticides and semi-volatiles testing by EPA methods demonstrates high resolution and quality of analysis

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Application guide to PFAS analysis in drinking water by EPA methods 533 and 537.1, from sample preparation to LC-MS/MS analysis, featuring both validated and exploratory methods.

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The latest applications and resources for testing cannabis potency, pesticides, mycotoxins, terpenes, and residual solvents.

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Novel sample preparation technique to reduce sample preparation time, material cost, and labor cost, thereby increasing laboratory productivity and sample throughput

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Get the answers to the PFAS most common analytical challenges on sample collection, extraction, methods, and decontamination procedures to ensure PFAS quality analysis.

Executive Summary

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We show the separation of tacrolimus from its related substances following Ph. Eur. monograph 2244 using the Luna 3 µm C18(2) and Luna Omega µm.

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We report the separation of diazoxide and its related organic impurities using a Kinetex ™2.6 µm biphenyl column according to the USP monograph for diazoxide.

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This step-by-step selectivity guide is an overview of the reversed-phase HPLC/UHPLC options available to you, highlighting the differences between the columns.

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LC–UV assay and organic impurities for paliperidone drug substance based on USP monograph where a L1 (C18) column with 100 x 4.6 mm, 3 µm dimensions was used