LCGC Europe-10-01-2019

The optimization of adjustable factors in electrospray ionization (ESI) by design of experiments (DoE) is presented. This approach allows a comprehensive and systematic optimization of all relevant factors for the ionization of compounds and increases the understanding about factor influences on the ionization efficiency.

The 48th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2019), chaired by Alberto Cavazzini and Massimo Morbidelli, was held from 16–20 June in Milan, Italy. This instalment of “Column Watch” covers many of the highlights observed at the symposium.

Retention of peptides is strongly dependent on solvent composition in reversed-phase separations with gradient elution. In this instalment we provide tips, tricks, and suggestions for best practices to help minimize retention time variations over time.

This article investigates host cell protein analysis using micro-pillar array columns combined with mass spectrometry.

The 13th International Scientific Conference on Ion Chromatography and Related Techniques will be held 21–22 April 2020 in Zabrze, Poland.

An excerpt from LCGC’s professional development platform, CHROMacademy.com

Click the title above to open the LCGC Europe October 2019 regular issue, Volume 32, Number 9, in an interactive PDF format.

LCGC Europe spoke to Zhanfei Liu from the Marine Science Institute at the University of Texas at Austin, Texas USA, about the advantages of ramped pyrolysis GC–MS to analyze petroleum pollution from the Deepwater Horizon oil spill.