LCGC North America-06-01-2002

LCGC North America

A Four-Column Approach to Developing Stability-Indicating HPLC Methods

June 01, 2002

Article

20

6

This article describes a method development approach that uses different packing materials and mobile-phase pH levels to optimize the chromatographic separation of degradation products from active ingredients.

Gas Cylinder Safety, Part I — Hazards and Precautions

June 01, 2002

GC Connections

20

6

John Hinshaw examines the principal safety issues surrounding the handling and use of compressed gas cylinders.

The Importance of Temperature

June 01, 2002

3

20

6

John Dolan focuses on several aspects of column temperature, which can affect retention, selectivity, peak shape, and column pressure.

Phase Collapse in Reversed-Phase Liquid Chromatography

June 01, 2002

Column Watch

20

6

The authors suggest ways to avoid phase collapse and regenerate collapsed phases.