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Sponsored Video: WITec

Since its' founding in 1997, WITec has established itself as a market leader in the field of nano-analytical microscope systems (Raman, AFM, SNOM). As reflected in WITec?s maxim "Focus Innovations", our success is based on constantly introducing new technologies and a commitment to maintaining customer satisfaction through high-quality, flexible and innovative products.

Split/splitless injectors typically vaporise a sample dissolved in a suitable organic solvent under increased temperature. The sample vapours are entrained into the carrier gas flow inside a "liner" or "sleeve" within the inlet and from there pass into the column or out of the inlet via "split" line / valve. Splitless injection is used to perform an "on-instrument" dilution and the relative amounts of sample which enter the column or discarded to waste via the split line are adjusted using the relative carrier and split flow rate ratio.

Let you quickly resolve and identify amino acid modifications in primary structure. These advanced biocolumns feature a 120A pore size with superficially porous 2.7 μm particles. They are specially tested with a challenging peptides mix to ensure reliable peptide mapping performance. In addition, AdvanceBio Peptide Mapping columns deliver exceptional resolution and speed for UHPLC, and excellent results for conventional HPLC too.

A new candidate biomarker of sugar and sugar-sweetened beverage (SSB) intake has been proposed in a recent study published in the Journal of Nutrition.1 The study presents the carbon isotope ratio of alanine as a new biomarker for use in studies monitoring dietary sugar intake

Sigma-Aldrich (Missouri, USA) has announced that it has partnered with The Scripps Research Institute (TSRI) (California, USA) to speed up access to discoveries by TSRI scientists to synthesize and analyze potential drugs. The partnership is the first to be formed between an academic institution and a reagents company.

Peaks of Interest

Trajan Scientific and Medical Acquires Chromatography and Liquid Handling Business Areas of SGE Analytical Science

Fava beans are a good source of polyphenols and are located in different parts of the plant. Phenolic compounds are thought to contribute to the overall antioxidant activities of plant foods. However, there is a lack of information on the phenolic composition of the seeds (beans) of some edible varieties. This has led a team of researchers based in Chile and Spain to use high performance liquid chromatography (HPLC) to identify the composition of a variety of immature fava seeds.

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LCGC spoke to Ana Mar?a Garc?a Campa?a about the issues and the development of techniques associated with monitoring veterinary drug residues in foods for human consumption.

Fatty acids found in fish oils have been linked to health benefits, but declining fish stocks and possible presence of contaminants, such as PCBs, dioxins, and methylmercury, in fish oil have led to a search for new sources.

This month we take a look at the important topic of buffer choice for HPLC separations, how to the choose the correct buffer type and concentration as well as how to avoid variability in retention and selectivity.

A cell cycle clock consisting of four continuous stages governs cell division (and replication), with each stage controlled by a specific series of protein complexes. Cancer is characterized by the uncontrolled division of cells that have gained genetic mutations that allow them to overcome these controls, therefore resulting in their self-sufficiency.